Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits

Y Zhang, IA Kerman, A Laque, P Nguyen… - Journal of …, 2011 - Soc Neuroscience
Brown adipose tissue (BAT) thermogenesis is critical to maintain homoeothermia and is
centrally controlled via sympathetic outputs. Body temperature and BAT activity also impact …

An immune paradox: how can the same chemokine axis regulate both immune tolerance and activation? CCR6/CCL20: a chemokine axis balancing immunological …

…, M Turvey, J Brazzatti, C Gregor, P Nguyen… - …, 2010 - Wiley Online Library
Chemokines (chemotactic cytokines) drive and direct leukocyte traffic. New evidence
suggests that the unusual CCR6/CCL20 chemokine receptor/ligand axis provides key homing …

Venetoclax induces rapid elimination of NPM1 mutant measurable residual disease in combination with low‐intensity chemotherapy in acute myeloid leukaemia

…, R Dillon, A Ivey, TC Teh, P Nguyen… - British journal of …, 2021 - Wiley Online Library
Based on promising results in older adults with acute myeloid leukaemia (AML), we treated
patients with NPM1 mut measurable residual disease (MRD) using off‐label venetoclax in …

[HTML][HTML] Medicines quality assurance to fight antimicrobial resistance

J Nwokike, A Clark, PP Nguyen - Bulletin of the World Health …, 2018 - ncbi.nlm.nih.gov
International Development (USAID) and implemented by the United States Pharmacopeia.
These approaches can be integrated into activities already included in global strategies and …

Designing protease-triggered protein cages

…, NP Dharmaraj, A Liu, PL Nguyen… - Journal of the …, 2022 - ACS Publications
Proteins that self-assemble into enclosed polyhedral cages, both naturally and by design,
are garnering attention for their prospective utility in the fields of medicine and biotechnology. …

[HTML][HTML] Global access to quality-assured medical products: the Oxford statement and call to action

…, B Naughton, T Ndorbor, A Nebot, P Nguyen… - The Lancet Global …, 2019 - thelancet.com
Substandard and falsified medical products (including medicines, vaccines, biologics, and
diagnostics1) repre sent a significant and growing threat to human health. Substandard …

Calcipotriol targets LRP6 to inhibit Wnt signaling in pancreatic cancer

MD Arensman, P Nguyen, KM Kershaw, AR Lay… - Molecular cancer …, 2015 - AACR
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy in need of more
effective treatment approaches. One potential therapeutic target is Wnt/β-catenin signaling, …

Accelerated thrombolysis and reperfusion in a canine model of myocardial infarction by liposomal encapsulation of streptokinase.

PD Nguyen, EA O'rear, AE Johnson… - Circulation …, 1990 - Am Heart Assoc
The aim of thrombolytic therapy for acute myocardial infarction with plasminogen activators
such as streptokinase is to lyse the coronary thrombus and reestablish blood flow as quickly …

[HTML][HTML] Submassive pulmonary embolism: current perspectives and future directions

PC Nguyen, H Stevens, K Peter… - Journal of Clinical …, 2021 - mdpi.com
Submassive pulmonary embolism (PE) lies on a spectrum of disease severity between
standard and high-risk disease. By definition, patients with submassive PE have a worse …

Enhancing fracture conductivity through surface modification of proppant

PD Nguyen, JD Weaver, BT Dewprashad… - … and Exhibition on …, 1998 - onepetro.org
Society of Petroleum Engineers Abstract A new liquid surface-modification system has been
developed for coating proppant, dramatically increasing its surface friction and allowing it to …