Mesolimbic dopamine-releasing neurons appear to be important in the brain reward system
1 , 2 . One behavioural paradigm that supports this hypothesis is intracranial self-stimulation …

Many of the molecules involved in biological signaling processes are easily oxidized and have
been monitored by electrochemical methods. Temporal response, spatial considerations, …

Thin films of overoxidized polypyrrole have been electrochemically coated onto carbon fiber
microelectrodes and used for dopamine measurements with background-subtracted, fast-…

Background and rationale Epidemiological evidence suggests that people who begin
experimenting with drugs of abuse during early adolescence are more likely to develop substance …

Previous data indicate that dopamine neurotransmission is differently regulated in male and
female rats. The purpose of the present study was to investigate the dopamine transporter …

Dihydrexidine (DHX), the first high-affinity D 1 dopamine receptor full agonist, is only 10-fold
selective for D 1 versus D 2 receptors, having D 2 affinity similar to the prototypical agonist …

Receptor-mediated feedback control plays an important role in dopamine (DA) neurotransmission.
Recent evidence suggests that release and uptake, key mechanisms determining …

Sex differences in biological substrates of drug use and addiction are poorly understood. The
present study investigated sexual dimorphisms in motor behavior following acute cocaine …

Adolescence is the developmental epoch during which children become adults—intellectually,
physically, hormonally and socially. Brain development in critical areas is ongoing. …

The present study tested the hypothesis that normal concentrations of extracellular dopamine
are preserved in the partially denervated striatum without active compensatory changes in …