CXCR6/CXCL16 functions as a regulator in metastasis and progression of cancer

L Deng, N Chen, Y Li, H Zheng, Q Lei - Biochimica et Biophysica Acta (BBA …, 2010 - Elsevier
Metastasis is considered the obvious mark for most aggressive cancers. However, little is
known about the molecular mechanism of the regulation of cancer metastasis. Recent …

[HTML][HTML] Higher mortality in lung cancer patients with COVID-19? A systematic review and meta-analysis

H Lei, Y Yang, W Zhou, M Zhang, Y Shen, D Tao… - Lung Cancer, 2021 - Elsevier
Highlights • This study summarized the mortality of lung cancer patients and other tumors
patients complicated by COVID-19. • The global mortality showed no significant difference. • …

[HTML][HTML] Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors

…, J Yang, G Xu, W Wang, C Liu, H Yang, Z Yu, Q Lei… - Oncotarget, 2015 - ncbi.nlm.nih.gov
MicroRNA-381 (miR-381) is a highly expressed onco-miRNA that is involved in malignant
progression and has been suggested to be a good target for glioblastoma multiforme (GBM) …

[HTML][HTML] LINC00470 coordinates the epigenetic regulation of ELFN2 to distract GBM cell autophagy

C Liu, H Fu, X Liu, Q Lei, Y Zhang, X She, Q Liu, Q Liu… - Molecular Therapy, 2018 - cell.com
The epigenetics and genomics of glioblastoma (GBM) are complicated. Previous reports
indicate that ELFN2 is widely distributed in the cerebral cortex neurons, striatum, and …

[HTML][HTML] miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma

X She, Z Yu, Y Cui, Q Lei, Z Wang, G Xu… - Oncology …, 2014 - spandidos-publications.com
Glioblastoma multiforme (GBM) is one of the most deadly diseases affecting humans, and is
often characterized by poor survival and by high resistance to chemotherapy and …

[HTML][HTML] Downregulation of miR-221-3p and upregulation of its target gene PARP1 are prognostic biomarkers for triple negative breast cancer patients and associated …

L Deng, Q Lei, Y Wang, Z Wang, G Xie, X Zhong… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The purpose of this study was to identify microRNAs (miRNAs) closely associated with the
prognosis of triple-negative breast cancer (TNBC) and their possible targets. This study …

miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells

X She, Z Yu, Y Cui, Q Lei, Z Wang, G Xu, Z Luo, G Li… - Medical Oncology, 2014 - Springer
Glioblastoma multiforme (GBM) is the most malignant and frequent brain tumor, with an
aggressive growth pattern and poor prognosis despite best treatment modalities. Although …

[HTML][HTML] Identification of potential crucial genes and key pathways in osteosarcoma

J Liu, S Wu, X Xie, Z Wang, Q Lei - Hereditas, 2020 - Springer
Background The aim of this study is to identify the potential pathogenic and metastasis-related
differentially expressed genes (DEGs) in osteosarcoma through bioinformatic analysis of …

[HTML][HTML] MiR-101 reverses the hypomethylation of the LMO3 promoter in glioma cells

X Liu, Q Lei, Z Yu, G Xu, H Tang, W Wang, Z Wang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
LIM-only protein 3 (LMO3), a member of the LIM-only protein group, is a new DNA methylation
gene that was identified in gliomas via the MeDIP-Chip in our previous study. In this study, …

[HTML][HTML] miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells

Q Lei, X Liu, H Fu, Y Sun, L Wang, G Xu, W Wang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Our previous report identified PR domain containing 16 (PRDM16), a member of the PR-domain
gene family, as a new methylation associated gene in astrocytoma cells. This previous …