Selective T-type calcium channel block in thalamic neurons reveals channel redundancy and physiological impact of ITwindow
…, VN Uebele, V Crunelli, RC Lambert… - Journal of …, 2010 - Soc Neuroscience
Although it is well established that low-voltage-activated T-type Ca 2+ channels play a key
role in many neurophysiological functions and pathological states, the lack of selective and …
role in many neurophysiological functions and pathological states, the lack of selective and …
Essential thalamic contribution to slow waves of natural sleep
Slow waves represent one of the prominent EEG signatures of non-rapid eye movement (non-REM)
sleep and are thought to play an important role in the cellular and network plasticity …
sleep and are thought to play an important role in the cellular and network plasticity …
Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early adulthood. …
because of their non-convulsive nature and the large incidence of remittance in early adulthood. …
Dual function of thalamic low-vigilance state oscillations: rhythm-regulation and plasticity
…, F David, SW Hughes, RC Lambert… - Nature Reviews …, 2018 - nature.com
During inattentive wakefulness and non-rapid eye movement (NREM) sleep, the neocortex
and thalamus cooperatively engage in rhythmic activities that are exquisitely reflected in the …
and thalamus cooperatively engage in rhythmic activities that are exquisitely reflected in the …
[HTML][HTML] From sleep spindles of natural sleep to spike and wave discharges of typical absence seizures: is the hypothesis still valid?
N Leresche, RC Lambert, AC Errington… - Pflügers Archiv-European …, 2012 - Springer
The temporal coincidence of sleep spindles and spike-and-wave discharges (SWDs) in
patients with idiopathic generalized epilepsies, together with the transformation of spindles into …
patients with idiopathic generalized epilepsies, together with the transformation of spindles into …
Cortical drive and thalamic feed-forward inhibition control thalamic output synchrony during absence seizures
…, Z Atherton, G Recchia, G Orban, RC Lambert… - Nature …, 2018 - nature.com
Behaviorally and pathologically relevant cortico-thalamo-cortical oscillations are driven by
diverse interacting cell-intrinsic and synaptic processes. However, the mechanism that gives …
diverse interacting cell-intrinsic and synaptic processes. However, the mechanism that gives …
T-type calcium channels consolidate tonic action potential output of thalamic neurons to neocortex
The thalamic output during different behavioral states is strictly controlled by the firing modes
of thalamocortical neurons. During sleep, their hyperpolarized membrane potential allows …
of thalamocortical neurons. During sleep, their hyperpolarized membrane potential allows …
[PDF][PDF] Layer 2/3 pyramidal neurons control the gain of cortical output
…, SL Fayad, K Boutourlinsky, N Leresche, RC Lambert… - Cell reports, 2018 - cell.com
Initial anatomical and physiological studies suggested that sensory information relayed from
the periphery by the thalamus is serially processed in primary sensory cortical areas. It is …
the periphery by the thalamus is serially processed in primary sensory cortical areas. It is …
Distinct kinetics of cloned T‐type Ca2 + channels lead to differential Ca2 + entry and frequency‐dependence during mock action potentials
…, E Perez‐Reyes, A Feltz, RC Lambert - European Journal of …, 1999 - Wiley Online Library
Voltage‐dependent activity around the resting potential is determinant in neuronal physiology
and participates in the definition of the firing pattern. Low‐voltage‐activated T‐type Ca 2 + …
and participates in the definition of the firing pattern. Low‐voltage‐activated T‐type Ca 2 + …
The many faces of T-type calcium channels
RC Lambert, T Bessaďh, V Crunelli… - Pflügers Archiv-European …, 2014 - Springer
Since the discovery of low-voltage-activated T-type calcium channels in sensory neurons
and the initial characterization of their physiological function mainly in inferior olive and …
and the initial characterization of their physiological function mainly in inferior olive and …