Epilepsy is one of the most frequent neurological diseases. In focal medically refractory
epilepsies, successful surgical treatment largely depends on the identification of epileptogenic …

High‐frequency oscillations (HFOs) in the 80–200 Hz range can be recorded from normal
hippocampus and parahippocampal structures of humans and animals. They are believed to …

… Ca 2+ indicators are bright, come in a wide variety of colors and have great signal to noise
ratios (R S/N ). The dyes can be easily loaded into cells in a noninvasive manner using their …

… Rows (top to bottom) depict activity in scalp EEG (Cz), right supplementary motor area (R-SMA),
left entorhinal cortex (L-EC), right … There was a strong tendency (r = 0.79; p << 1 3 10 …

… Results of the “goodness of fit” of the curve to observed values were R 2 = 0.94 (df. = 25)
and analysis of the residuals revealed a Kolmogorov-Smirnov distance of 0.22 (P > 0.10), …

Sleep spindles are an electroencephalographic (EEG) hallmark of non-rapid eye movement
(NREM) sleep and are believed to mediate many sleep-related functions, from memory …

The presence of fast ripple oscillations (FRs, 200–500Hz) has been confirmed in rodent
epilepsy models but has not been observed in nonepileptic rodents, suggesting that FRs are …

Unique high‐frequency oscillations of 250 to 500Hz, termed fast ripples, have been identified
in seizure‐generating limbic areas in rats made epileptic by intrahippocampal injection of …

The neurochemical changes underlying human emotions and social behaviour are largely
unknown. Here we report on the changes in the levels of two hypothalamic neuropeptides, …

Neurosurgery is an underutilized treatment that can potentially cure drug‐refractory epilepsy.
Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to ensure …