User profiles for Rabih Moshourab

rabih moshourab

Max Delbrück Centrum
Verified email at mdc-berlin.de
Cited by 1938

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

SS Ranade, SH Woo, AE Dubin, RA Moshourab… - Nature, 2014 - nature.com
The sense of touch provides critical information about our physical environment by transforming
mechanical energy into electrical signals 1 . It is postulated that mechanically activated …

A stomatin-domain protein essential for touch sensation in the mouse

…, A Benckendorff, L Harder, A Eilers, R Moshourab… - Nature, 2007 - nature.com
Touch and mechanical pain are first detected at our largest sensory surface, the skin. The
cell bodies of sensory neurons that detect such stimuli are located in the dorsal root ganglia, …

Mechanosensation and pain

GR Lewin, R Moshourab - Journal of neurobiology, 2004 - Wiley Online Library
The ability of cells to detect and transduce mechanical stimuli impinging on them is a
fundamental process that underlies normal cell growth, hearing, balance, touch, and pain. …

[HTML][HTML] Photoswitchable fatty acids enable optical control of TRPV1

JA Frank, M Moroni, R Moshourab, M Sumser… - Nature …, 2015 - nature.com
Fatty acids (FAs) are not only essential components of cellular energy storage and structure,
but play crucial roles in signalling. Here we present a toolkit of photoswitchable FA …

USH2A is a Meissner's corpuscle protein necessary for normal vibration sensing in mice and humans

…, G García-García, FJ Taberner, R Moshourab… - Nature …, 2021 - nature.com
Fingertip mechanoreceptors comprise sensory neuron endings together with specialized
skin cells that form the end-organ. Exquisitely sensitive, vibration-sensing neurons are …

Stomatin‐domain protein interactions with acid‐sensing ion channels modulate nociceptor mechanosensitivity

RA Moshourab, C Wetzel… - The Journal of …, 2013 - Wiley Online Library
Key points • Gene deletion studies revealed that membrane proteins stomatin and STOML3,
as well as the acid‐sensing ion channels ASIC2 and ASIC3, regulate mechanosensory …

Role of T-type calcium current in identified D-hair mechanoreceptor neurons studied in vitro

…, C Martinez-Salgado, R Moshourab… - Journal of …, 2004 - Soc Neuroscience
Different subsets of dorsal root ganglion (DRG) mechanoreceptors transduce low- and high-intensity
mechanical stimuli. It was shown recently that, in vivo, neurotrophin-4 (NT-4)-…

Speed and temperature dependences of mechanotransduction in afferent fibers recorded from the mouse saphenous nerve

…, C Wetzel, R Moshourab… - Journal of …, 2008 - journals.physiology.org
Here we have systematically characterized the stimulus response properties of mechanosensitive
sensory fibers in the mouse saphenous nerve. We tested mechanoreceptors and …

Incidence and linguistic quality of speech errors: a comparison of preoperative transcranial magnetic stimulation and intraoperative direct cortex stimulation

…, MR Muench, H Schneider, R Moshourab… - Journal of …, 2020 - thejns.org
OBJECTIVE Given the interindividual variance of functional language anatomy, risk prediction
based merely on anatomical data is insufficient in language area–related brain tumor …

[HTML][HTML] A molecular signature of myalgia in myotonic dystrophy 2

R Moshourab, V Palada, S Grunwald, U Grieben… - …, 2016 - thelancet.com
Background Chronic muscle pain affects close to 20% of the population and is a major
health burden. The underlying mechanisms of muscle pain are difficult to investigate as pain …