[PDF][PDF] Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain

…, MA Koike, NN Dagher, EE Spangenberg, RA Rice… - Neuron, 2014 - cell.com
The colony-stimulating factor 1 receptor (CSF1R) is a key regulator of myeloid lineage cells.
Genetic loss of the CSF1R blocks the normal population of resident microglia in the brain …

Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology

EE Spangenberg, RJ Lee, AR Najafi, RA Rice… - Brain, 2016 - academic.oup.com
In addition to amyloid-β plaque and tau neurofibrillary tangle deposition, neuroinflammation
is considered a key feature of Alzheimer’s disease pathology. Inflammation in Alzheimer's …

Elimination of microglia improves functional outcomes following extensive neuronal loss in the hippocampus

RA Rice, EE Spangenberg… - Journal of …, 2015 - Soc Neuroscience
With severe injury or disease, microglia become chronically activated and damage the local
brain environment, likely contributing to cognitive decline. We previously discovered that …

Microglial repopulation resolves inflammation and promotes brain recovery after injury

RA Rice, J Pham, RJ Lee, AR Najafi, BL West… - Glia, 2017 - Wiley Online Library
Microglia mediate chronic neuroinflammation following central nervous system (CNS) disease
or injury, and in doing so, damage the local brain environment by impairing recovery and …

[HTML][HTML] CSF1 receptor signaling is necessary for microglia viability, which unmasks a cell that rapidly repopulates the microglia-depleted adult brain

…, MA Koike, NN Dagher, EE Spangenberg, RA Rice… - Neuron, 2014 - ncbi.nlm.nih.gov
The colony stimulating factor 1 receptor (CSF1R) is a key regulator of myeloid lineage cells.
Genetic loss of the CSF1R blocks the normal population of resident microgliain the brain that …

Age-related downregulation of the CaV3. 1 T-type calcium channel as a mediator of amyloid beta production

RA Rice, NC Berchtold, CW Cotman, KN Green - Neurobiology of aging, 2014 - Elsevier
Alzheimer's is a crippling neurodegenerative disease that largely affects aged individuals.
Decades of research have highlighted age-related changes in calcium homeostasis that occur …

Characteristics of Kelvin–Helmholtz waves as observed by the MMS from September 2015 to March 2020

RC Rice, K Nykyri, X Ma… - Journal of Geophysical …, 2022 - Wiley Online Library
The Magnetospheric Multiscale (MMS) mission has presented a new opportunity to study the
fine scale structures and phenomena of the Earth’s magnetosphere, including cross scale …

Comparison between fluid simulation with test particles and hybrid simulation for the Kelvin‐Helmholtz instability

…, B Burkholder, B Neupane, RC Rice - Journal of …, 2019 - Wiley Online Library
A quantitative investigation of plasma transport rate via the Kelvin‐Helmholtz (KH) instability
can improve our understanding of solar‐wind‐magnetosphere coupling processes. …

Probing 3′-ssDNA loop formation in E. coli RecBCD/RecBC–DNA complexes using non-natural DNA: a model for “Chi” recognition complexes

CJ Wong, RL Rice, NA Baker, T Ju… - Journal of molecular …, 2006 - Elsevier
The equilibrium binding of Escherichia coli RecBC and RecBCD helicases to duplex DNA
ends containing varying lengths of polyethylene glycol (PEG) spacers within pre-formed 3′-…

[HTML][HTML] Inter-and transgenerational heritability of preconception chronic stress or alcohol exposure: Translational outcomes in brain and behavior

RC Rice, DV Gil, AM Baratta, RR Frawley, SY Hill… - Neurobiology of …, 2023 - Elsevier
Chronic stress and alcohol (ethanol) use are highly interrelated and can change an individual’s
behavior through molecular adaptations that do not change the DNA sequence, but …