We report the first identification of a cellular receptor mediating entry of a gram-positive
bacterium into nonphagocytotic cells. By an affinity chromatography approach, we identified E-…

The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on the …

Force sensing at cadherin-mediated adhesions is critical for their proper function. α-Catenin,
which links cadherins to actomyosin, has a crucial role in this mechanosensing process. It …

A major form of animal cell–cell adhesion results from the dynamic association of cadherin
molecules, cytosolic catenins and actin microfilaments. Cadherins dynamically regulate the …

Matrix rigidity sensing regulates a large variety of cellular processes and has important
implications for tissue development and disease. However, how cells probe matrix rigidity, and …

Background information. Mechanical forces play an important role in the organization,
growth and function of living tissues. The ability of cells to transduce mechanical signals is …

The cadherin-catenin adhesion complex is the key component of the intercellular adherens
junction (AJ) that contributes both to tissue stability and dynamic cell movements in epithelial …

Type IV pili mediate the initial interaction of many bacterial pathogens with their host cells.
In Neisseria meningitidis, the causative agent of cerebrospinal meningitis, type IV pili–…

Maintaining cell cohesiveness within tissues requires that intercellular adhesions develop
sufficient strength to support traction forces applied by myosin motors and by neighboring cells…

The directed migration of cell collectives is essential in various physiological processes, such
as epiboly, intestinal epithelial turnover, and convergent extension during morphogenesis, …