Hypoxia—ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter

SA Back, A Craig, RJ Kayton, NL Luo… - Journal of Cerebral …, 2007 - journals.sagepub.com
Ischemia is implicated in periventricular white matter injury (PWMI), a lesion associated with
cerebral palsy. PWMI features selective damage to early cells of the oligodendrocyte lineage…

Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage

…, A Arshad, MTK Zia, F Hu, RJ Kayton… - Journal of …, 2013 - Soc Neuroscience
Intraventricular hemorrhage (IVH) remains a major cause of white matter injury in preterm
infants with no viable therapeutic strategy to restore myelination. Maturation of …

Ultrastructural immunolocalization of basic fibroblast growth factor in mast cell secretory granules: morphological evidence for bFGF release through degranulation

Z Qu, RJ Kayton, P Ahmadi, JM Liebler… - … of Histochemistry & …, 1998 - journals.sagepub.com
We previously reported that mast cells (MCs) serve as a source of basic fibroblast growth
factor (bFGF), a potent angiogenic and mitogenic polypeptide, suggesting that bFGF may …

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

…, GM Higgins, P Hurban, RJ Kayton… - Toxicological …, 2007 - academic.oup.com
Gene expression profiling is a widely used technique with data from the majority of
published microarray studies being publicly available. These data are being used for meta-analyses …

Bone morphogenetic protein inhibition promotes neurological recovery after intraventricular hemorrhage

…, A Csiszar, C Chua, P Mouton, RJ Kayton… - Journal of …, 2011 - Soc Neuroscience
Intraventricular hemorrhage (IVH) results in neural cell death and white matter injury in
premature infants. No therapeutic strategy is currently available against this disorder. Bone …

Age related optic nerve axonal loss in adult Brown Norway rats

WO Cepurna, RJ Kayton, EC Johnson… - Experimental eye …, 2005 - Elsevier
The effect of age on the number and morphology of optic nerve axons in adult Brown Norway
rats (5–31 months old) (n=29) was examined using transmission electron microscopy (TEM…

1, 2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy

MS Kim, MI Sabri, VH Miller, RJ Kayton… - Toxicology and applied …, 2001 - Elsevier
Several widely used aromatic hydrocarbon solvents reportedly induce blue-green discoloration
of tissues and urine in animals and humans. The chomophore has been proposed to …

On the biomarkers and mechanisms of konzo, a distinct upper motor neuron disease associated with food (cassava) cyanogenic exposure

…, NL Kasensa, VH Monterroso, RJ Kayton… - Food and chemical …, 2011 - Elsevier
Konzo is a self-limiting central motor-system disease associated with food dependency on
cassava and low dietary intake of sulfur amino acids (SAA). Under conditions of SAA-…

Neotropical Monogenoidea. 3. Five new species from South America with the proposal of Tereancistrum gen. n. and Trinibaculum gen. n.(Dactylogyridae …

DC Kritsky, VE Thatcher, RJ Kayton - Acta Amazonica, 1980 - SciELO Brasil
Five new species of Monogenoidea (Dactylogyridae: Ancyrocephalinae) are described from
the gills of freshwater fishes of South America: Jainus amazonensis sp. n., Tereancistrum …

Monocyclic and dicyclic hydrocarbons: structural requirements for proximal giant axonopathy

…, VS Palmer, MR Lasarev, RJ Kayton… - Acta …, 2006 - Springer
The chromogenic and neurotoxic γ-diketone 1,2–diacetylbenzene (1,2-DAB), but not its
isomer 1,3-DAB, induces blue discoloration of tissues and urine, clustering of axonal …