Infection-triggered perturbation of the immune system could induce psychopathology, and
psychiatric sequelae were observed after previous coronavirus outbreaks. The spreading of …

Widespread demyelination and axonal loss are the pathological hallmarks of multiple sclerosis.
The multifocal nature of this chronic inflammatory disease of the central nervous system …

In degenerative disorders of the central nervous system (CNS), transplantation of neural
multipotent (stem) precursor cells (NPCs) is aimed at replacing damaged neural cells 1 , 2 . …

COVID-19 outbreak is associated with mental health implications during viral infection and
at short-term follow-up. Data on psychiatric and cognitive sequelae at medium-term follow-up …

There is a long history of research into body fluid biomarkers in neurodegenerative and
neuroinflammatory diseases. However, only a few biomarkers in CSF are being used in clinical …

We have earlier shown that microglia, the immune cells of the CNS, release microparticles
from cell plasma membrane after ATP stimulation. These vesicles contain and release IL‐1β, …

Recent research has demonstrated that all body fluids assessed contain substantial amounts
of vesicles that range in size from 30 to 1000 nm and that are surrounded by phospholipid …

The secondary progressive phase of multiple sclerosis (MS), which is characterised by a
steady accrual of fixed disability after an initial relapsing remitting course, is not clearly …

Neurodegeneration is the irremediable pathological event occurring during chronic
inflammatory diseases of the CNS. Here we show that, in experimental autoimmune …

Background and objective: We explored which clinical and biochemical variables predict
conversion from clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS…