User profiles for Ruth E. Grunau

Ruth Grunau

university of british columbia
Verified email at cw.bc.ca
Cited by 29503

Procedural pain and brain development in premature newborns

S Brummelte, RE Grunau, V Chau, KJ Poskitt… - Annals of …, 2012 - Wiley Online Library
Objective: Preterm infants are exposed to multiple painful procedures in the neonatal intensive
care unit (NICU) during a period of rapid brain development. Our aim was to examine …

Long-term consequences of pain in human neonates

RE Grunau, L Holsti, JWB Peters - Seminars in Fetal and Neonatal …, 2006 - Elsevier
The low tactile threshold in preterm infants when they are in the neonatal intensive care unit
(NICU), while their physiological systems are unstable and immature, potentially renders …

Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants

RE Grunau, MF Whitfield, J Petrie-Thomas, AR Synnes… - Pain, 2009 - Elsevier
Procedural pain in the neonatal intensive care unit triggers a cascade of physiological,
behavioral and hormonal disruptions which may contribute to altered neurodevelopment in …

BrainNetCNN: Convolutional neural networks for brain networks; towards predicting neurodevelopment

…, CJ Brown, SP Miller, BG Booth, V Chau, RE Grunau… - NeuroImage, 2017 - Elsevier
We propose BrainNetCNN, a convolutional neural network (CNN) framework to predict
clinical neurodevelopmental outcomes from brain networks. In contrast to the spatially local …

Neonatal procedural pain exposure predicts lower cortisol and behavioral reactivity in preterm infants in the NICU

RE Grunau, L Holsti, DW Haley, T Oberlander… - Pain, 2005 - Elsevier
… Author links open overlay panel Ruth E. Grunau a b e , Liisa Holsti a d e , David W. Haley a
b , Tim Oberlander a b e , Joanne Weinberg a c , Alfonso Solimano b e , Michael F. Whitfield …

Survival without disability to age 5 years after neonatal caffeine therapy for apnea of prematurity

…, PJ Anderson, LW Doyle, D Dewey, RE Grunau… - Jama, 2012 - jamanetwork.com
Context Very preterm infants are prone to apnea and have an increased risk of death or
disability. Caffeine therapy for apnea of prematurity reduces the rates of cerebral palsy and …

[HTML][HTML] Impact of repeated procedural pain-related stress in infants born very preterm

J Vinall, RE Grunau - Pediatric research, 2014 - nature.com
The majority of infants born very preterm (24–32 wk gestational age) now survive; however,
long-term neurodevelopmental and behavioral problems remain a concern. As part of their …

Altered basal cortisol levels at 3, 6, 8 and 18 months in infants born at extremely low gestational age

RE Grunau, DW Haley, MF Whitfield, J Weinberg… - The Journal of …, 2007 - Elsevier
OBJECTIVE: Little is known about the developmental trajectory of cortisol levels in preterm
infants after hospital discharge. STUDY DESIGN: In a cohort of 225 infants (gestational age at …

Early childhood neurodevelopment after intrauterine growth restriction: a systematic review

TA Levine, RE Grunau, FM McAuliffe… - …, 2015 - publications.aap.org
BACKGROUND AND OBJECTIVE: Children who experienced intrauterine growth restriction
(IUGR) may be at increased risk for adverse developmental outcomes in early childhood. …

[HTML][HTML] Neonatal pain-related stress predicts cortical thickness at age 7 years in children born very preterm

…, K Fitzpatrick, AR Synnes, SP Miller, RE Grunau - PloS one, 2013 - journals.plos.org
Background Altered brain development is evident in children born very preterm (24–32 weeks
gestational age), including reduction in gray and white matter volumes, and thinner cortex, …