D2 Receptors May Modulate the Function of the Striatal Transporter for Dopamine: Kinetic Evidence from Studies In Vitro and In Vivo
SM Meiergerd, TA Patterson… - Journal of …, 1993 - Wiley Online Library
Recently it was hypothesized by others that the D 2 dopamine receptor can regulate the uptake
of dopamine. However, the evidence in support of this hypothesis, although compelling, …
of dopamine. However, the evidence in support of this hypothesis, although compelling, …
Individual locomotor response to novelty predicts selective alterations in D1 and D2 receptors and mRNAs
…, JL Juncos, JB Justice, SM Meiergerd… - Journal of …, 1994 - Soc Neuroscience
Rats that have a greater locomotor response to novelty (high responders, HR) have differences
in measures of presynaptic dopamine transmission compared to low responders (LR) to …
in measures of presynaptic dopamine transmission compared to low responders (LR) to …
Striatal transporter for dopamine: catechol structure‐activity studies and susceptibility to chemical modification
SM Meiergerd, JO Schenk - Journal of neurochemistry, 1994 - Wiley Online Library
The apparent second‐order association rate constant of dopamine binding to the striatal
transporter (∼1 ± 10 6 M −1 s −1 ) as well as the transporter turnover number (∼1.5 s −1 ) was …
transporter (∼1 ± 10 6 M −1 s −1 ) as well as the transporter turnover number (∼1.5 s −1 ) was …
Kinetic evaluation of the commonality between the site (s) of action of cocaine and some other structurally similar and dissimilar inhibitors of the striatal transporter for …
SM Meiergerd, JO Schenk - Journal of neurochemistry, 1994 - Wiley Online Library
… , 1989, 1990), and although it is larger than that published previously by others it has been
shown by a kinetic test of consistency to represent the same transport system (Meiergerd and …
shown by a kinetic test of consistency to represent the same transport system (Meiergerd and …
Relationships between the catechol substrate binding site and amphetamine, cocaine, and mazindol binding sites in a kinetic model of the striatal transporter of …
H Wayment, SM Meiergerd… - Journal of …, 1998 - Wiley Online Library
Experiments were conducted to determine how (−)‐cocaine and S(+)‐amphetamine binding
sites relate to each other and to the catechol substrate site on the striatal dopamine …
sites relate to each other and to the catechol substrate site on the striatal dopamine …
Repeated cocaine and stress increase dopamine clearance in the rat medial prefrontal cortex
SM Meiergerd, JO Schenk, BA Sorg - Brain research, 1997 - Elsevier
… The tissue was chopped and placed into 500 μl physiological buffer as described by Meiergerd
and Schenk [31]and maintained at 37C in a temperature-controlled chamber. The tissue …
and Schenk [31]and maintained at 37C in a temperature-controlled chamber. The tissue …
Effects of cocaine and repeated cocaine followed by withdrawal: alterations of dopaminergic transporter turnover with no changes in kinetics of substrate recognition
SM Meiergerd, JS McElvain, JO Schenk - Biochemical pharmacology, 1994 - Elsevier
… The TN and k~s values were estimated following the procedures outlined by Meiergerd
and Schenk [14] (which are based on the work of Fersht [15] and Stein [16]) using …
and Schenk [14] (which are based on the work of Fersht [15] and Stein [16]) using …
The striatal transporter for dopamine in the rat may be kinetically up‐regulated following 3 weeks of withdrawal from cocaine self‐administration
SM Meiergerd, SM Hooks… - Journal of …, 1994 - Wiley Online Library
… Experimental validation of this apparent kinetic condition was given by Meiergerd and
Schenk (1994a,b). The experiments with striatal suspensions prepared from CSECOC animals …
Schenk (1994a,b). The experiments with striatal suspensions prepared from CSECOC animals …
Measurement of the time-resolved kinetics of biogenic amine release and transporter activity by rotating disk electrode voltammetry in vitro
SM Meiergerd, JO Schenk - Voltammetric methods in brain systems, 1995 - Springer
… study of the transport of DA (Meiergerd and Schenk, 1994a). Subsequently, the numerical
value of k ass was confirmed by apparent presteady-state kinetics (Meiergerd et al., 1994b). …
value of k ass was confirmed by apparent presteady-state kinetics (Meiergerd et al., 1994b). …
[BOOK][B] Kinetic investigation of the dopamine transport system
SM Meiergerd - 1994 - search.proquest.com
… By SUSAN MARIE MEIERGERD … The members of the Committee appointed to examine the
dissertation of Susan Marie Meiergerd find it satisfactory and recommend that it be accepted. …
dissertation of Susan Marie Meiergerd find it satisfactory and recommend that it be accepted. …