Loss of FBXO 7 (PARK 15) results in reduced proteasome activity and models a parkinsonism‐like phenotype in mice
…, N Schwedhelm‐Domeyer, S Joseph… - The EMBO …, 2016 - embopress.org
Mutations in the FBXO 7 ( PARK 15) gene have been implicated in a juvenile form of
parkinsonism termed parkinsonian pyramidal syndrome ( PPS ), characterized by Parkinsonian …
parkinsonism termed parkinsonian pyramidal syndrome ( PPS ), characterized by Parkinsonian …
Mechanistic contributions of FBXO7 to Parkinson disease
S Joseph, JB Schulz, J Stegmüller - Journal of neurochemistry, 2018 - Wiley Online Library
Parkinson disease (PD) is, without doubt, a burden on modern society as the prevalence
increases significantly with age. Owing to this growing number of PD cases, it is more critical …
increases significantly with age. Owing to this growing number of PD cases, it is more critical …
Loss of the parkinsonism‐associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects
J Wang, S Joseph, S Vingill, E Dere… - Journal of …, 2023 - Wiley Online Library
Mutations in PARK15, which encodes for the F‐box protein FBXO7 have been associated
with Parkinsonian Pyramidal syndrome, a rare and complex movement disorder with …
with Parkinsonian Pyramidal syndrome, a rare and complex movement disorder with …
Myelinating glia-specific deletion of Fbxo7 in mice triggers axonal degeneration in the central nervous system together with peripheral neuropathy
S Joseph, S Vingill, O Jahn, R Fledrich… - Journal of …, 2019 - Soc Neuroscience
Myelination of axons facilitates the rapid propagation of electrical signals and the long-term
integrity of axons. The ubiquitin-proteasome system is essential for proper protein …
integrity of axons. The ubiquitin-proteasome system is essential for proper protein …
Gallyas silver impregnation of myelinated nerve fibers
S Joseph, HB Werner, J Stegmüller - Bio-protocol, 2019 - bio-protocol.org
In the nervous system of vertebrates, nerve impulse propagation is accelerated by the
ensheathment of neuronal axons with myelin. Myelin sheaths are molecularly specialized, lipid-…
ensheathment of neuronal axons with myelin. Myelin sheaths are molecularly specialized, lipid-…
[PDF][PDF] A novel role for the E3 ubiquitin ligase FBXO7 in axon-myelin interaction
SL Joseph - 2018 - pure.mpg.de
I further would like to highlight, how much I appreciate the incredible effort and immense
support that the coordinators (Prof. Dr. Michael Hörner and Sandra Drube) of the IMPRS …
support that the coordinators (Prof. Dr. Michael Hörner and Sandra Drube) of the IMPRS …
In-vitro and in-silico strategies to assess the unexplored pharmacological lineages of Solanum elaeagnifolium Cav. Leaves
The current work aims to investigate the chemical components in Solanum elaeagnifolium
leaf extracts and their pharmacological potential in antioxidant, antibacterial and anti-diabetic …
leaf extracts and their pharmacological potential in antioxidant, antibacterial and anti-diabetic …
Effectiveness of antenatal care package on knowledge of pregnancy induced hypertension for antenatal mothers in selected hospitals of mangalore
SJ Joseph, S Nayak, P Fernandes… - Journal of Health and …, 2013 - thieme-connect.com
The study was conducted on effectiveness of antenatal care package on knowledge of
pregnancy induced hypertension for antenatal mothers from 7/09/2009 to 10/10/2009. The …
pregnancy induced hypertension for antenatal mothers from 7/09/2009 to 10/10/2009. The …
[PDF][PDF] Evaluation of egg quality traits and cholesterol content of eggs of Aseel crossbreds
S Antony, L Joseph, PA Peethambaran, P Anitha - 2023 - thepharmajournal.com
An experiment was conducted to evaluate and compare the egg quality traits of eggs
obtained from hens of Aseel× Naked Neck (ANN), Aseel× New Hampshire (ANH) and Aseel× …
obtained from hens of Aseel× Naked Neck (ANN), Aseel× New Hampshire (ANH) and Aseel× …
[HTML][HTML] Stimuli-responsive polymeric nanosystem for colon specific drug delivery
SK Joseph, M Sabitha, SC Nair - Advanced pharmaceutical bulletin, 2020 - ncbi.nlm.nih.gov
An ideal colon specific drug delivery system needs to perform multiple functions like greater
bio availability, less toxicity and higher therapeutic efficacy, all of which require high degree …
bio availability, less toxicity and higher therapeutic efficacy, all of which require high degree …