Genetic evidence implicates a causal role for the complement pathway in Alzheimer’s disease
(AD). Since studies have shown inconsistent differences in cerebrospinal fluid (CSF) and …

Prions, which cause fatal neurodegenerative disorders such as Creutzfeldt‐Jakob disease,
are misfolded and infectious protein aggregates. Currently, there are no treatments available …

Corneal and ocular surface diseases (OSDs) carry significant psychosocial and economic
burden worldwide. We set out to review the literature on the application of artificial intelligence …

Background Studies suggest a role of the innate immune system, including the activity of
neutrophils, in neurodegeneration related to Alzheimer’s disease (AD), but prospective …

This systematic review explores the use of artificial intelligence (AI) in the analysis of biofluid
markers in age-related macular degeneration (AMD). We detail the accuracy and validity of …

Background: The endosomal-lysosomal and autophagy (ELA) pathway may be implicated
in the progression of Alzheimer’s disease (AD); however, findings thus far have been …

There is an urgent need to understand the relationships between amyloid-β (Aβ) and tau in
the progression of Alzheimer's disease to identify treatment targets. Here we examine …

Purpose This scoping review summarizes the applications of artificial intelligence (AI) and
bioinformatics methodologies in analysis of ocular biofluid markers. The secondary objective …

Purpose This study aims to identify the available literature describing the utilization of artificial
intelligence (AI) as a clinical tool in uveal diseases. Methods A comprehensive literature …

Longitudinal invariance indicates that a construct is measured over time in the same way, and
this fundamental scale property is a sine qua non to track change over time using ordinary …