Mice deficient for δ-and μ-opioid receptors exhibit opposing alterations of emotional responses
D Filliol, S Ghozland, J Chluba, M Martin… - Nature …, 2000 - nature.com
The role of the opioid system in controlling pain 1, reward and addiction 2, 3 is well
established, but its role in regulating other emotional responses is poorly documented in …
established, but its role in regulating other emotional responses is poorly documented in …
Motivational effects of cannabinoids are mediated by μ-opioid and κ-opioid receptors
S Ghozland, HWD Matthes, F Simonin… - Journal of …, 2002 - Soc Neuroscience
Repeated THC administration produces motivational and somatic adaptive changes leading
to dependence in rodents. To investigate the molecular basis for cannabinoid dependence …
to dependence in rodents. To investigate the molecular basis for cannabinoid dependence …
CRF–CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats
O George, S Ghozland, MR Azar… - Proceedings of the …, 2007 - National Acad Sciences
Nicotine, the main psychoactive ingredient of tobacco, induces negative emotional
symptoms during abstinence that contribute to a profound craving for nicotine. However, the …
symptoms during abstinence that contribute to a profound craving for nicotine. However, the …
The glucocorticoid receptor as a potential target to reduce cocaine abuse
…, R Izawa, M Jaber, S Ghozland… - Journal of …, 2003 - Soc Neuroscience
Several findings suggest that glucocorticoid hormones are involved in determining the
propensity of an individual to develop cocaine abuse. These hormones activate two related …
propensity of an individual to develop cocaine abuse. These hormones activate two related …
Nicotine withdrawal in adolescent and adult rats
LE O'DELL, AW Bruijnzeel, S Ghozland… - Annals of the New …, 2004 - Wiley Online Library
Previous research with animal models has demonstrated that adolescent rats display heightened
sensitivity to the reinforcing and stimulant effects of nicotine relative to adult rats. Little …
sensitivity to the reinforcing and stimulant effects of nicotine relative to adult rats. Little …
Lack of stimulant and anxiolytic-like effects of ethanol and accelerated development of ethanol dependence in mu-opioid receptor knockout mice
S Ghozland, K Chu, BL Kieffer, AJ Roberts - Neuropharmacology, 2005 - Elsevier
The opioid system is implicated in various aspects of alcoholism. Acute ethanol administration
produces anxiolytic-like effects in rodents while alcohol withdrawal induces anxiogenic-…
produces anxiolytic-like effects in rodents while alcohol withdrawal induces anxiogenic-…
Effects of nandrolone on acute morphine responses, tolerance and dependence in mice
E Célérier, MT Yazdi, A Castañé, S Ghozland… - European journal of …, 2003 - Elsevier
Anabolic–androgenic steroid exposure has been proposed to present a risk factor for the
misuse of other drugs of abuse. We now examined whether the exposure to the anabolic–…
misuse of other drugs of abuse. We now examined whether the exposure to the anabolic–…
[HTML][HTML] Disruption of the CRF2 receptor pathway decreases the somatic expression of opiate withdrawal
F Papaleo, S Ghozland, M Ingallinesi… - …, 2008 - nature.com
Escape from the extremely aversive opiate withdrawal symptoms powerfully motivates
compulsive drug-seeking and drug-taking behaviors. The corticotropin-releasing factor (CRF) …
compulsive drug-seeking and drug-taking behaviors. The corticotropin-releasing factor (CRF) …
Spontaneous network activity of cerebellar granule neurons: impairment by in vivo chronic cannabinoid administration
S Ghozland, F Aguado… - European Journal of …, 2002 - Wiley Online Library
Synchronized activity of neuronal networks has been proposed to be essential for cerebellar
function. To examine the occurrence and organization of spontaneous neuronal activity in …
function. To examine the occurrence and organization of spontaneous neuronal activity in …
Scheduling process at DEA‐the example of cannabidiol
SG Ghozland, JM Tolliver, SM Carr, CA Sannerud - 2008 - Wiley Online Library
DEA collects and reviews scientific, medical and other data on substances to determine
their abuse potential and placement into the Controlled Substances Act (CSA). The scientific …
their abuse potential and placement into the Controlled Substances Act (CSA). The scientific …