Drugs of abuse dynamically regulate adult neurogenesis, which appears important for some
types of learning and memory. Interestingly, a major site of adult neurogenesis, the …

Prefrontal cortical executive functions comprise a number of cognitive capabilities
necessary for goal directed behavior and adaptation to a changing environment. Executive …

Deficits in cognitive flexibility, the ability to modify behavior in response to changes in the
environment, contribute to the onset and maintenance of stress-related neuropsychiatric …

Ginseng, the root of Panax ginseng CA Meyer (Araliaceae), is a widely used herbal medicine.
Ginsenosides, the active ingredients of ginseng, are the main components responsible for …

Astronauts traveling to Mars will be exposed to chronic low doses of galactic cosmic space
radiation, which contains highly charged, high-energy (HZE) particles. Fe-HZE-particle …

Post-traumatic stress disorder (PTSD) is a debilitating illness characterized by dysfunction
in the medial prefrontal cortex (mPFC). Although both pharmacological and cognitive …

Adult dentate gyrus (DG) neurogenesis is important for hippocampal‐dependent learning and
memory, but the role of new neurons in addiction‐relevant learning and memory is unclear…

Chronic stress compromises cognition, including executive function mediated in the medial
prefrontal cortex (mPFC). To investigate mechanisms underlying these processes, we use …

Opiates – including morphine – are powerful analgesics with high abuse potential. In
rodents, chronic opiate exposure or self-administration negatively impacts hippocampal-dependent …

Previous work has suggested that the peptide corticotropin-releasing factor (CRF) acts to
inhibit visually guided feeding in anurans, but little is known about potential targets for CRF …