Dysregulation of mTOR signaling in fragile X syndrome
…, Y Takayasu, T Miyawaki, SM McBride… - Journal of …, 2010 - Soc Neuroscience
Fragile X syndrome, the most common form of inherited mental retardation and leading
genetic cause of autism, is caused by transcriptional silencing of the Fmr1 gene. The fragile X …
genetic cause of autism, is caused by transcriptional silencing of the Fmr1 gene. The fragile X …
Clinically localized prostate cancer: AUA/ASTRO guideline, part I: introduction, risk assessment, staging, and risk-based management
…, CJ Kane, E Kirkby, DW Lin, SM McBride… - Journal of …, 2022 - journals.lww.com
Purpose: The summary presented herein represents Part I of the three-part series dedicated
to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing risk assessment, …
to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing risk assessment, …
Hypofractionated stereotactic body radiotherapy in low‐risk prostate adenocarcinoma: Preliminary results of a multi‐institutional phase 1 feasibility trial
SM McBride, DS Wong, JJ Dombrowski, B Harkins… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Recent reports using extreme hypofractionated regimens in the treatment
of low‐risk prostate adenocarcinoma have been encouraging. Here, the authors report on …
of low‐risk prostate adenocarcinoma have been encouraging. Here, the authors report on …
The molecular landscape of recurrent and metastatic head and neck cancers: insights from a precision oncology sequencing platform
…, SG Patel, BR Roman, CA Barker, SM McBride… - JAMA …, 2017 - jamanetwork.com
Importance Recurrent and/or metastatic head and neck cancer is usually incurable.
Implementation of precision oncology for these patients has been limited by incomplete …
Implementation of precision oncology for these patients has been limited by incomplete …
A systematic review of the evidence for the decipher genomic classifier in prostate cancer
… Sean M. McBride—research funding from Janssen and Genentech, and honoraria from
AstraZeneca. Shuang G. Zhao—patent applications with Decipher biosciences on molecular …
AstraZeneca. Shuang G. Zhao—patent applications with Decipher biosciences on molecular …
[HTML][HTML] Prostate cancer radiation therapy recommendations in response to COVID-19
Purpose During a global pandemic, the benefit of routine visits and treatment of patients with
cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is …
cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is …
Clinically localized prostate cancer: AUA/ASTRO guideline, part II: principles of active surveillance, principles of surgery, and follow-up
…, CJ Kane, E Kirkby, DW Lin, SM McBride… - Journal of …, 2022 - journals.lww.com
Purpose: The summary presented herein represents Part II of the three-part series dedicated
to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing principles of …
to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing principles of …
Patterns of treatment failure and postrecurrence outcomes among patients with locally advanced head and neck squamous cell carcinoma after chemoradiotherapy …
…, E Katsoulakis, E Lupovitch, SM McBride… - JAMA …, 2017 - jamanetwork.com
Importance Even though 15% to 50% of patients with head and neck squamous cell carcinoma
(HNSCC) experience recurrence, relatively little is known regarding patterns of treatment …
(HNSCC) experience recurrence, relatively little is known regarding patterns of treatment …
Evaluation of substantial reduction in elective radiotherapy dose and field in patients with human papillomavirus–associated oropharyngeal carcinoma treated with …
Importance Several de-escalation strategies for human papillomavirus (HPV)–associated
oropharyngeal carcinoma (OPC) have focused on deintensifying gross disease treatment. …
oropharyngeal carcinoma (OPC) have focused on deintensifying gross disease treatment. …
PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome
…, E Romero, S Zheng, JK Wiencke, SM McBride… - Neuro …, 2012 - academic.oup.com
The signaling pathways that underlie the pathogenesis of pediatric gliomas are poorly
understood. We characterized the PI3K/Akt/mTOR pathway in pediatric gliomas of all grades. …
understood. We characterized the PI3K/Akt/mTOR pathway in pediatric gliomas of all grades. …