It has been hypothesized that alcohol addiction is mediated, at least in part, by specific γ-aminobutyric
acid A (GABA A) receptors within the ventral pallidum (VP). Among the potential …

We investigated the potential role of the α 1 -containing GABA A receptor in regulating the
reinforcing properties of alcohol. To accomplish this, we developed 3-propoxy-β-carboline …

GABA receptors within the mesolimbic circuitry have been proposed to play a role in regulating
alcohol-seeking behaviors in the alcohol-preferring (P) rat. However, the precise GABA A …

Rationale: Given that alcoholics drink for different reasons, it is not likely that a single
pharmacotherapeutic agent will be equally effective for all alcoholics. Hence, the development of …

The exact opioid-sensitive receptors participating in EtOH-seeking behaviors remains
unclear. Previous studies have reported higher densities of μ-opioid receptor binding in the …

Nalmefene, the 6‐methylene derivative of naltrexone, was examined after subcutaneous (sc)
(0.0001 to 8.0 mg/kg) and oral (10 to 80.0 mg/kg) administration in ethanol (EtOH)‐…

Rationale Previously, we reported that the GABA A receptor containing α 5 subunit played a
significant role in the reinforcing actions of EtOH in rats selectively bred to consume alcohol. …

Background: Previous research has implicated the α5‐containing GABA A receptors of the
hippocampus in the reinforcing properties of alcohol. In the present study, a selective GABA A …

The purpose of the present study is to examine the relationships among medication compliance
with diuretic therapy, health-related quality of life (HRQL) and disease outcomes in heart …

Graduate students are eligible to participate in Commencement if they have completed all
requirements for their degrees during the previous year. The roster of candidates listed in this …