Reprogramming somatic cells to a pluripotent state drastically reconfigures the cellular anabolic
requirements, thus potentially inducing cancer-like metabolic transformation. Accordingly…

The regulated turnover of synaptic vesicle (SV) proteins is thought to involve the ubiquitin-dependent
tagging and degradation through endo-lysosomal and autophagy pathways. Yet, it …

Schnitzler's syndrome is a rare autoinflammatory disorder characterized by interleukin-1ß-mediated
and neutrophil-dominated inflammation. Neutrophil extracellular traps (NETs) are …

Abstract Information on protein–protein interactions ( PPI s) is of critical importance for studying
complex biological systems and developing therapeutic strategies. Here, we present a …

Mechanisms regulating the turnover of synaptic vesicle (SV) proteins are not well understood.
They are thought to require poly-ubiquitination and degradation through proteasome, endo…

Maintaining the integrity and function of the presynaptic neurotransmitter release apparatus
is a demanding process for a post-mitotic neuron; the mechanisms behind it are still unclear. …

Piccolo, a presynaptic active zone protein, is best known for its role in the regulated assembly
and function of vertebrate synapses. Genetic studies suggest a further link to several …

The regulated turnover of synaptic vesicle (SV) proteins is thought to involve the ubiquitin-
dependent tagging and degradation of SV proteins through endo-lysosomal and autophagy …

Piccolo, a presynaptic active zone protein, is best known for its role in the regulated assembly
and function of vertebrate synapses. Genetic studies suggest a further link to several …

The regulated turnover of synaptic vesicle (SV) proteins is thought to involve the ubiquitin
dependent tagging and degradation through endo-lysosomal and autophagy pathways. Yet, it …