User profiles for Shigeyuki Esumi
 | Esumi ShigeyukiAssitant Professor/ Lecturer, Graduate School of Medicine, Kumamoto University Verified email at kumamoto-u.ac.jp Cited by 1129 |
Monoallelic yet combinatorial expression of variable exons of the protocadherin-α gene cluster in single neurons
S Esumi, N Kakazu, Y Taguchi, T Hirayama, A Sasaki… - Nature …, 2005 - nature.com
Diverse protocadherin-α genes (Pcdha, also called cadherin-related neuronal receptor or
CNR) are expressed in the vertebrate brain. Their genomic organization involves multiple …
CNR) are expressed in the vertebrate brain. Their genomic organization involves multiple …
[HTML][HTML] Allelic gene regulation of Pcdh-α and Pcdh-γ clusters involving both monoallelic and biallelic expression in single Purkinje cells
R Kaneko, H Kato, Y Kawamura, S Esumi… - Journal of Biological …, 2006 - ASBMB
The molecular basis for providing the identity and diversity of single neurons is a key for
realizing the brain system. Diverse protocadherin isoforms encoded by the Pcdh-α and Pcdh-γ …
realizing the brain system. Diverse protocadherin isoforms encoded by the Pcdh-α and Pcdh-γ …
The protocadherin-α family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse
Olfactory sensory neurons (OSNs) that express the same odorant receptor project their axons
to specific glomeruli in the main olfactory bulb. Protocadherin-α (Pcdha) proteins, diverse …
to specific glomeruli in the main olfactory bulb. Protocadherin-α (Pcdha) proteins, diverse …
[HTML][HTML] SPP1 derived from macrophages is associated with a worse clinical course and chemo-resistance in lung adenocarcinoma
E Matsubara, Y Komohara, S Esumi, Y Shinchi… - Cancers, 2022 - mdpi.com
Simple Summary Osteopontin, also called secreted phosphoprotein 1 (SPP1), is expressed
by cancer cells and is known as a poor prognostic factor. Although the production of SPP1 …
by cancer cells and is known as a poor prognostic factor. Although the production of SPP1 …
Macrophage/microglia-derived IL-1β induces glioblastoma growth via the STAT3/NF-κB pathway
K Kai, Y Komohara, S Esumi, Y Fujiwara, T Yamamoto… - Human Cell, 2022 - Springer
Glioblastoma is a glioma characterized by highly malignant features. Numerous studies
conducted on the relationship between glioblastoma and the microenvironment have indicated …
conducted on the relationship between glioblastoma and the microenvironment have indicated …
α1-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
K Matsusaka, Y Fujiwara, C Pan, S Esumi, Y Saito, J Bi… - Cancer Research, 2021 - AACR
… Shigeyuki Esumi; Shigeyuki Esumi … Esumi: Data curation, formal analysis, investigation,
visualization, methodology. Y. Saito: Data curation, formal analysis, investigation, methodology. …
visualization, methodology. Y. Saito: Data curation, formal analysis, investigation, methodology. …
Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues
10.7554/eLife.21012.001 The medial subnucleus of the amygdala (MeA) plays a central role
in processing sensory cues required for innate behaviors. However, whether there is a link …
in processing sensory cues required for innate behaviors. However, whether there is a link …
Method for single-cell microarray analysis and application to gene-expression profiling of GABAergic neuron progenitors
S Esumi, SX Wu, Y Yanagawa, K Obata… - Neuroscience …, 2008 - Elsevier
The mammalian central nervous system is populated with various types of neurons and glia.
To investigate the functions and development of individual cells requires gene-expression …
To investigate the functions and development of individual cells requires gene-expression …
[PDF][PDF] Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1
The hypothalamus integrates information required for the production of a variety of innate
behaviors such as feeding, mating, aggression, and predator avoidance. Despite an extensive …
behaviors such as feeding, mating, aggression, and predator avoidance. Despite an extensive …
[HTML][HTML] Constitutively expressed Protocadherin-α regulates the coalescence and elimination of homotypic olfactory axons through its cytoplasmic region
…, T Hirabayashi, T Kondo, K Inoue, S Esumi… - Frontiers in molecular …, 2012 - frontiersin.org
Olfactory sensory neuron (OSN) axons coalesce into specific glomeruli in the olfactory bulb (OB)
according to their odorant receptor (OR) expression. Several guidance molecules …
according to their odorant receptor (OR) expression. Several guidance molecules …