[HTML][HTML] miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway

J Li, S Donath, Y Li, D Qin, BS Prabhakar, P Li - PLoS genetics, 2010 - journals.plos.org
miRNAs participate in the regulation of apoptosis. However, it remains largely unknown as
to how miRNAs are integrated into the apoptotic program. Mitochondrial fission is involved in …

On the single processor performance of simple lattice Boltzmann kernels

G Wellein, T Zeiser, G Hager, S Donath - Computers & Fluids, 2006 - Elsevier
This report presents a comprehensive survey of the effect of different data layouts on the
single processor performance characteristics for the lattice Boltzmann method both for …

WaLBerla: HPC software design for computational engineering simulations

C Feichtinger, S Donath, H Köstler, J Götz… - Journal of Computational …, 2011 - Elsevier
WaLBerla (Widely applicable Lattice-Boltzmann from Erlangen) is a massively parallel
software framework supporting a wide range of physical phenomena. This article describes the …

Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress

S Donath, P Li, C Willenbockel, N Al-Saadi, V Gross… - Circulation, 2006 - Am Heart Assoc
Background— Ischemic heart disease and heart failure are associated with an increased loss
of cardiomyocytes due to apoptosis. Whether cardiomyocyte apoptosis plays a causal role …

Behaviorally conditioned immunosuppression using cyclosporine A: central nervous system reduces IL-2 production via splenic innervation

…, M Schult, J Vöge, T Strubel, S Donath… - Journal of …, 1998 - Elsevier
Bi-directional interactions between the central nervous system (CNS) and immune system
are demonstrated by the modification of immune function using behavioral conditioning. …

ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity

J An, P Li, J Li, R Dietz, S Donath - Journal of Molecular Medicine, 2009 - Springer
Despite its complexity of action, doxorubicin (Dox)-induced cardiomyopathy eventually
results in loss of cardiac myocytes which further contributes to the development of overt heart …

[PDF][PDF] TAT‐apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure

…, A Heuser, M Endres, C Trautwein, S Donath - …, 2012 - Wiley Online Library
Acute liver failure (ALF) is associated with massive hepatocyte cell death and high mortality
rates. Therapeutic approaches targeting hepatocyte injury in ALF are hampered by the …

ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosis

…, M Li, G Sellge, AD Mandić, C Trautwein, S Donath - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: Acetaminophen (AAP) overdose is the most frequent cause of drug-induced
liver failure. c-Jun N-terminal kinase (JNK) is thought to play a central role in AAP-…

Coupling multibody dynamics and computational fluid dynamics on 8192 processor cores

J Götz, K Iglberger, C Feichtinger, S Donath, U Rüde - Parallel Computing, 2010 - Elsevier
This paper describes a method for the fully resolved simulation of particle laden flows. For
this purpose, we discuss the parallelization of large scale coupled fluid structure interaction …

Conditioned immunosuppression makes subtherapeutic cyclosporin effective via splenic innervation

MS Exton, M Schult, S Donath… - American Journal …, 1999 - journals.physiology.org
The present study investigated the mechanisms by which conditioned immunosuppression
enhances the effectiveness of cyclosporin A (CsA) treatment in prolonging heart allograft …