To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19 and
the current standard care relies on supportive treatments. Therefore, based on the fast and …

Expansion of a polyglutamine sequence in the N terminus of huntingtin is the gain-of-function
event that causes Huntington's disease. This mutation affects primarily the medium-size …

The term “circadian rhythms” describes endogenous oscillations with ca. 24-h period associated
with the earth’s daily rotation and light/dark cycle. Such rhythms reflect the existence of …

The microbiota is a complex ecosystem of microorganisms consisting of bacteria, viruses,
protozoa, and fungi, living in different districts of the human body, such as the gastro-enteric …

The therapeutic approach for improving the cognitive function in patients with Alzheimer’s
disease (AD) is mainly based on the potentiation of central cholinergic activity and is achieved …

There is a recent growing evidence that abnormalities in the microbiota composition can
have a major role in the development of obesity and diabetes and that some actions of …

Memory, attention and creativity represent three different cognitive domains, which are
interconnected and contribute the “mental performance” of an individual. Modern neuroscience …

Roughly ten years ago the FDA approved most of the presently used anti-VEGF drugs for
the treatment of neovascular AMD and other eye pathologies characterized by ocular …

Several lines of biochemical evidence correlate the presence of energy metabolic defects
with the functional alterations associated with brain aging and with the pathogenesis of …

The specific antiradical activity against the hydroxyl radical of the water soluble components
in green and dark roasted Coffea arabica and Coffea robusta coffee samples, both in vitro …