Fluorescence resonance energy transfer (FRET) technology has been used to develop
genetically encoded fluorescent indicators for various cellular functions. Although most indicators …

Associating temporally discontinuous elements is crucial for the formation of episodic and
working memories that depend on the hippocampal-entorhinal network. However, the neural …

Defensins comprise a family of cationic antimicrobial peptides that are characterized by the
presence of six conserved cysteine residues. We identified two novel human β-defensin (hBD…

Formation of neurofibrillary tangles (NFTs) is a common neuropathological feature found in
several neurodegenerative diseases, including Alzheimer's disease. We have developed a …

The entorhinal cortex provides the major cortical input to the hippocampus, and both structures
have been implicated in memory processes. The dynamics of neuronal circuits in the …

We have quantified the optical signals of synaptically induced neural activities in an in vitro
brain slice preparation in terms of electrophysiological signals. The qualification was done …

Prenatal exposure to valproic acid (VPA), an established antiepileptic drug, has been reported
to impair postnatal cognitive function in children born to VPA-treated epileptic mothers. …

Protein tyrosine phosphatase 1B (PTP1B) regulates leptin signaling in hypothalamic
neurons via the JAK2-STAT3 pathway. PTP1B has also been implicated in the regulation of …

JC polyomavirus (JCV) is a ubiquitous symbiote in the human population, infecting children
asymptomatically and then persisting in renal tissue. We reevaluated the urinary excretion of …

PURPOSE: Renal cell carcinoma is sometimes associated with bone metastasis. Several
risk factors have been reported but some are still controversial. Also, the significance of …