Smaller amygdala is associated with anxiety in patients with panic disorder

…, T Yoshida, T Roppongi, T Otsuka… - Psychiatry and …, 2009 - Wiley Online Library
Aims: Anxiety a core feature of panic disorder, is linked to function of the amygdala. Volume
alterations in the brain of patients with panic disorder have previously been reported, but …

Differential contributions of prefrontal and hippocampal dopamine D1 and D2 receptors in human cognitive functions

…, R Arakawa, M Okumura, T Otsuka… - Journal of …, 2008 - Soc Neuroscience
Dopamine D 1 receptors in the prefrontal cortex (PFC) are important for prefrontal functions,
and it is suggested that stimulation of prefrontal D 1 receptors induces an inverted U-shaped …

Anterior cingulate cortex volume reduction in patients with panic disorder

…, H Yamasue, K Uehara, T Otsuka… - Psychiatry and …, 2008 - Wiley Online Library
Aim: Recent neuroimaging studies have suggested that the anterior cingulate cortex (ACC)
has an important role in the pathology of panic disorder. Despite numerous functional …

Sexually dimorphic gray matter volume reduction in patients with panic disorder

…, F Hayano, M Nakamura, K Uehara, T Otsuka… - Psychiatry Research …, 2009 - Elsevier
While clinical features of panic disorder show significant sexual dimorphism, previous
structural MRI studies have not sufficiently controlled for sex when looking at regional brain …

Initial and progressive gray matter abnormalities in insular gyrus and temporal pole in first-episode schizophrenia contrasted with first-episode affective psychosis

SH Lee, M Niznikiewicz, T Asami, T Otsuka… - Schizophrenia …, 2016 - academic.oup.com
Although the insula and temporal pole (TP) of paralimbic regions are important in both
affective and cognitive processing, it is not well known whether gray matter volume (GMV) …

Association between social participation and incident risk of functional disability in elderly Japanese: The Ohsaki Cohort 2006

T Otsuka, Y Tomata, S Zhang, K Sugiyama… - Journal of …, 2018 - Elsevier
Background Although several longitudinal studies have examined the relationship between
social participation and incident functional disability, the related mechanisms have remained …

Posterior orbitofrontal sulcogyral pattern associated with orbitofrontal cortex volume reduction and anxiety trait in panic disorder

…, T Asami, F Hayano, T Otsuka… - Psychiatry and …, 2010 - Wiley Online Library
Aims: The posterior region of the orbitofrontal cortex (OFC), which forms its sulcogyral pattern
during neurodevelopment, receives multisensory inputs. The purpose of the present study …

[HTML][HTML] Psychological distress and completed suicide in Japan: A comparison of the impact of moderate and severe psychological distress

F Tanji, Y Tomata, S Zhang, T Otsuka, I Tsuji - Preventive medicine, 2018 - Elsevier
It has already been established that severe psychological distress is a major risk factor for
completed suicide. However, the impact (population attributable fraction; PAF) of moderate …

Exploratory eye movement dysfunction as a discriminator for schizophrenia: a large sample study using a newly developed digital computerized system

…, H Maeda, S Katayama, R Kawahara, T Otsuka… - European archives of …, 2009 - Springer
In our previous studies, we identified that exploratory eye movement (EEM) dysfunction
appears to be specific to schizophrenia. The availability of a biological marker specific to …

Contribution of dopamine D1 and D2 receptors to amygdala activity in human

…, R Arakawa, M Yamada, T Otsuka… - Journal of …, 2010 - Soc Neuroscience
Several animal studies have demonstrated functional roles of dopamine (DA) D1 and D2
receptors in amygdala activity. However, the contribution of DA D1 and D2 receptors to …