Thepresent study employed event-related fMRI and EEG to investigate the biological basis
of the cognitive control of behavior. Using a GO/NOGO task optimized to produce response …

OBJECTIVE: Cocaine-related cues have been hypothesized to perpetuate drug abuse by
inducing a craving response that prompts drug-seeking behavior. However, the mechanisms, …

Although extensive evidence exists for the reinforcing properties of drugs of abuse such as
cocaine, relatively less research has addressed the functional neuroanatomical correlates of …

Human lesion and functional imaging data suggest a central role for the amygdala in the
processing of negative stimuli. To determine whether the amygdala's role in affective …

Drug addiction is a public health crisis for which new treatments are urgently needed. In rare
cases, regional brain damage can lead to addiction remission. These cases may be used to …

Understanding nicotine's neurobiological and cognitive mechanisms may help explain both
its addictive properties and potential therapeutic applications. As such, functional MRI was …

Sustained attention deficits occur in several neuropsychiatric disorders. However, the underlying
neurobiological mechanisms are still incompletely understood. To that end, functional …

Midline brain activation subsequent to errors has been proposed to reflect error detection
and, alternatively, conflict-monitoring processes. Adjudicating between these alternatives is …

Preclinical models have consistently demonstrated the importance of the mesocorticolimbic (MCL)
brain reward system in drug dependence, with critical molecular and cellular …

Context Understanding the mechanisms underlying nicotine addiction to develop more
effective treatment is a public health priority. Research consistently shows that nicotine …