Abnormalities in functional connectivity between brain areas have been postulated as an
important pathophysiological mechanism underlying schizophrenia 1 , 2 . In particular, …

The hippocampus and prefrontal cortex (PFC) have long been known to play a central role
in various behavioral and cognitive functions. More recently, electrophysiological and …

Many of the sounds that we perceive are caused by our own actions, for example when
speaking or moving, and must be distinguished from sounds caused by external events. Studies …

The rodent medial prefrontal cortex (mPFC) is critical for spatial working memory (SWM), but
the underlying neural processes are incompletely understood. During SWM tasks, neural …

The prefrontal cortex (PFC) enables a staggering variety of complex behaviors, such as
planning actions, solving problems, and adapting to new situations according to external …

Much of the research on long-term potentiation (LTP) is motivated by the question of
whether changes in synaptic strength similar to LTP underlie learning and memory. Here we …

10.7554/eLife.38818.001 Extinction of fear responses is critical for adaptive behavior and
deficits in this form of safety learning are hallmark of anxiety disorders. However, the neuronal …

Researchers performing multi-site recordings are often interested in identifying the directionality
of functional connectivity and estimating lags between sites. Current techniques for …

BACKGROUND: Like fear conditioning, the acquisition phase of extinction involves new
learning that is mediated by the amygdala. During extinction training, the conditioned stimulus is …

Long‐term memory underlying Pavlovian fear conditioning is believed to involve plasticity at
sensory input synapses in the lateral nucleus of the amygdala (LA). A useful physiological …