T-type Ca2+ channels boost neurotransmission in mammalian cone photoreceptors
A Davison, UT Lux, JH Brandstätter… - Journal of …, 2022 - Soc Neuroscience
It is a commonly accepted view that light stimulation of mammalian photoreceptors causes a
graded change in membrane potential instead of developing a spike. The presynaptic Ca 2…
graded change in membrane potential instead of developing a spike. The presynaptic Ca 2…
[HTML][HTML] Light-dependent regulation of neurotransmitter release from rod photoreceptor ribbon synapses involves an interplay of Complexin 4 and Transducin with the …
UT Lux, J Meyer, O Jahn, A Davison… - Frontiers in Molecular …, 2024 - frontiersin.org
Adaptation of photoreceptor sensitivity to varying light intensities is a fundamental requirement
for retinal function and vision. Adaptive mechanisms in signal transduction are well …
for retinal function and vision. Adaptive mechanisms in signal transduction are well …
[HTML][HTML] The first synapse in vision in the aging mouse retina
K Gierke, UT Lux, H Regus-Leidig… - Frontiers in Cellular …, 2023 - frontiersin.org
Vision is our primary sense, and maintaining it throughout our lifespan is crucial for our well-being.
However, the retina, which initiates vision, suffers from an age-related, irreversible …
However, the retina, which initiates vision, suffers from an age-related, irreversible …
[HTML][HTML] Lack of a retinal phenotype in a Syne-2/Nesprin-2 knockout mouse model
N Falk, A Joachimsthaler, K Kessler, UT Lux… - Cells, 2019 - mdpi.com
Syne-2 (also known as Nesprin-2) is a member of a family of proteins that are found
primarily in the outer nuclear membrane, as well as other subcellular compartments. Syne-2 …
primarily in the outer nuclear membrane, as well as other subcellular compartments. Syne-2 …
[HTML][HTML] Cell Types and Synapses Expressing the SNARE Complex Regulating Proteins Complexin 1 and Complexin 2 in Mammalian Retina
UT Lux, J Ehrenberg, A Joachimsthaler, J Atorf… - International Journal of …, 2021 - mdpi.com
Complexins (Cplxs) 1 to 4 are components of the presynaptic compartment of chemical synapses
where they regulate important steps in synaptic vesicle exocytosis. In the retina, all four …
where they regulate important steps in synaptic vesicle exocytosis. In the retina, all four …
Light Adaptation of Rod Photoreceptor Synapses by a Transducin-Complexin-SNARE Complex Interaction
Adaptation of photoreceptor sensitivity to varying light intensities is a fundamental requirement
for retinal function and thus for vision. Photoreceptors transduce light into neuronal signals…
for retinal function and thus for vision. Photoreceptors transduce light into neuronal signals…
[HTML][HTML] A novel calcium channel Cavβ2 splice variant with unique properties predominates in the retina
…, P Grabher, J Hartl, L Zanetti, UT Lux… - Journal of Biological …, 2023 - ASBMB
Cavβ subunits are essential for surface expression of voltage-gated calcium channel complexes
and crucially modulate biophysical properties like voltage-dependent inactivation. Here, …
and crucially modulate biophysical properties like voltage-dependent inactivation. Here, …
[HTML][HTML] AGO recommendations for the surgical therapy of breast cancer: update 2022
Die Empfehlungen der AGO Kommission Mamma zur operativen Therapie des Mammakarzinoms
wurden zuletzt im März 2022 aktualisiert (www.ago-online.de). Da die operative …
wurden zuletzt im März 2022 aktualisiert (www.ago-online.de). Da die operative …
[HTML][HTML] Axillary staging after neoadjuvant chemotherapy for initially node-positive breast carcinoma in Germany
…, E Stickeler, M Thill, MP Lux… - Geburtshilfe und …, 2022 - thieme-connect.com
Einleitung Das optimale axilläre Stagingverfahren für initial nodal positive
MammakarzinompatientInnen nach neoadjuvanter Chemotherapie (NACT) ist bislang unklar. Die …
MammakarzinompatientInnen nach neoadjuvanter Chemotherapie (NACT) ist bislang unklar. Die …
AGO-Empfehlungen zur operativen Therapie des Mammakarzinoms: Update 2022
Die Empfehlungen der AGO-Kommission Mamma zur operativen Therapie des Mammakarzinoms
wurden zuletzt im März 2022 aktualisiert (www.ago-online.de). Da die operative …
wurden zuletzt im März 2022 aktualisiert (www.ago-online.de). Da die operative …