Iron is a key nutrient for normal central nervous system (CNS) development and function;
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS. …

Previous studies have implicated DTNBP1 as a schizophrenia susceptibility gene and its
encoded protein, dysbindin, as a potential regulator of synaptic vesicle physiology. In this study…

We have previously shown that the expression of voltage-operated Ca ++ channels (VOCCs)
is highly regulated in the oligodendroglial lineage and is essential for proper …

To determine whether L-type voltage-operated Ca 2+ channels (L-VOCCs) are required for
oligodendrocyte progenitor cell (OPC) development, we generated an inducible conditional …

We have found a significant upregulation of L‐type voltage‐operated Ca ++ channels (VOCCs)
in reactive astrocytes. To test if VOCCs are centrally involved in triggering astrocyte …

To determine whether Cav1.2 voltage-gated Ca 2+ channels contribute to astrocyte activation,
we generated an inducible conditional knock-out mouse in which the Cav1.2 α subunit …

Exploring the molecular mechanisms that drive the maturation of oligodendrocyte progenitor
cells (OPCs) during the remyelination process is essential to developing new therapeutic …

To test the hypothesis that the transferrin (Tf) cycle has unique importance for oligodendrocyte
development and function, we disrupted the expression of the Tf receptor (Tfr) gene in …

Biogenesis of lysosome-related organelles complex 1 (BLOC-1) is a protein complex formed
by the products of eight distinct genes. Loss-of-function mutations in two of these genes, …

The divalent metal transporter 1 (DMT1) is a multimetal transporter with a primary role in iron
transport. Although DMT1 has been described previously in the CNS, nothing was known …