In chordates, formation of neural tissue from ectodermal cells requires an induction. The
molecular nature of the inducer remains controversial in vertebrates. Here, using the early …

Background The prospects of deciphering the genetic program underlying embryonic
development were recently boosted by the generation of large sets of precisely organized …

How asymmetric divisions are connected to the terminal differentiation program of neuronal
subtypes is poorly understood. In C. elegans, two homeodomain transcription factors, TTX-3 (…

Lineage-based mechanisms are widely used to generate cell type diversity in both vertebrates
and invertebrates. For the past few decades, the nematode Caenorhabditis elegans has …

Our understanding of the maternal factors that initiate early chordate development, and of
their direct zygotic targets, is still fragmentary. A molecular cascade is emerging for the …

Whole-genome sequencing (WGS) of organisms displaying a specific mutant phenotype is a
powerful approach to identify the genetic determinants of a plethora of biological processes…

Ascidian embryos develop with a fixed cell lineage into simple tadpoles. Their lineage is
almost perfectly conserved, even between the evolutionarily distant species Halocynthia roretzi …

Transcription factors of the TCF family are key mediators of the Wnt/β-catenin pathway. TCF
usually activates transcription on cis-regulatory elements containing TCF binding sites when …

Wnt/β-catenin signalling has been implicated in the terminal asymmetric divisions of neuronal
progenitors in vertebrates and invertebrates. However, the role of Wnt ligands in this …

This paper analyses the potential of biomass-based electricity in the EU-27 countries, and
interactions with climate policy and the EU ETS. We estimate the potential biomass demand …