[HTML][HTML] Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential

…, A Uygur, Y Hayakawa, S Gross, BW Renz, W Setlik… - Cell, 2015 - cell.com
The stem cells that maintain and repair the postnatal skeleton remain undefined. One model
suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise to osteoblasts, …

[PDF][PDF] Regulation of presynaptic neurotransmission by macroautophagy

D Hernandez, CA Torres, W Setlik, C Cebrián… - Neuron, 2012 - cell.com
mTOR is a regulator of cell growth and survival, protein synthesis-dependent synaptic
plasticity, and autophagic degradation of cellular components. When triggered by mTOR …

[PDF][PDF] Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche

…, K Nagar, H Tomita, A Hara, AR Sepulveda, W Setlik… - Cancer cell, 2015 - cell.com
The regulation and stem cell origin of normal and neoplastic gastric glands are uncertain.
Here, we show that Mist1 expression marks quiescent stem cells in the gastric corpus isthmus. …

Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size

…, DE Krantz, Y Liu, JW Haycock, W Setlik… - Journal of …, 2000 - Soc Neuroscience
While the transporters that accumulate classical neurotransmitters in synaptic vesicles have
been identified, little is known about how their expression regulates synaptic transmission. …

Enteric glia regulate gastrointestinal motility but are not required for maintenance of the epithelium in mice

M Rao, D Rastelli, L Dong, S Chiu, W Setlik… - Gastroenterology, 2017 - Elsevier
Background & Aims When the glial fibrillary acidic protein (GFAP) promoter is used to express
cellular toxins that eliminate glia in mice, intestinal epithelial permeability and proliferation …

Expression and function of 5-HT4 receptors in the mouse enteric nervous system

M Liu, MS Geddis, Y Wen, W Setlik… - American Journal of …, 2005 - journals.physiology.org
The aim of the current study was to identify enteric 5-HT 4 splice variants, locate enteric 5-HT
4 receptors, determine the relationship, if any, of the 5-HT 4 receptor to 5-HT 1P activity, …

Stimulation‐dependent regulation of the pH, volume and quantal size of bovine and rodent secretory vesicles

EN Pothos, E Mosharov, KP Liu, W Setlik… - The Journal of …, 2002 - Wiley Online Library
Trapping of weak bases was utilized to evaluate stimulus‐induced changes in the internal
pH of the secretory vesicles of chromaffin cells and enteric neurons. The internal acidity of …

[HTML][HTML] Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice

…, E Pakarinen, T Danilova, TD Pham, W Setlik… - Neurobiology of …, 2020 - Elsevier
Cerebral dopamine neurotrophic factor (CDNF) is neuroprotective for nigrostriatal dopamine
neurons and restores dopaminergic function in animal models of Parkinson's disease (PD). …

Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling

…, Y Shang, TD Pham, I Hsieh, W Setlik… - Journal of …, 2011 - Soc Neuroscience
Trophic factor signaling is important for the migration, differentiation, and survival of enteric
neurons during development. The mechanisms that regulate the maturation of enteric …

[HTML][HTML] Long-lived intestinal tuft cells serve as colon cancer–initiating cells

…, AH Nuber, A Brandtner, W Setlik… - The Journal of …, 2014 - Am Soc Clin Investig
Doublecortin-like kinase 1 protein (DCLK1) is a gastrointestinal tuft cell marker that has been
proposed to identify quiescent and tumor growth–sustaining stem cells. DCLK1 + tuft cells …