User profiles for Wataru Mizunoya

Wataru Mizunoya

Azabu University
Verified email at azabu-u.ac.jp
Cited by 4668

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

…, A Oku, K Tsuda, S Toyokuni, H Hiai, W Mizunoya… - Nature medicine, 2002 - nature.com
Secretion of gastric inhibitory polypeptide (GIP), a duodenal hormone, is primarily induced by
absorption of ingested fat. Here we describe a novel pathway of obesity promotion via GIP. …

[HTML][HTML] FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

…, T Shibakusa, W Mizunoya… - The Journal of …, 2008 - Am Soc Clin Investig
White adipocytes are unique in that they contain large unilocular lipid droplets that occupy
most of the cytoplasm. To identify genes involved in the maintenance of mature adipocytes, …

Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase

…, A Nagasawa, W Mizunoya… - Proceedings of the …, 2005 - National Acad Sciences
In adipocytes, hydrolysis of triglycerides results in the release of free fatty acids and glycerol.
Aquaporin 7 (AQP7), a member of aquaglyceroporins, is known to permeabilize glycerol …

High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing …

…, S Shiratsuchi, A Sato, W Mizunoya… - … of Physiology-Cell …, 2010 - journals.physiology.org
Skeletal muscle regeneration and work-induced hypertrophy rely on molecular events
responsible for activation and quiescence of resident myogenic stem cells, satellite cells. Recent …

Matrix metalloproteinase-2 mediates stretch-induced activation of skeletal muscle satellite cells in a nitric oxide-dependent manner

M Yamada, Y Sankoda, R Tatsumi, W Mizunoya… - The international journal …, 2008 - Elsevier
When skeletal muscle is stretched or injured, myogenic satellite cells are activated to enter
the cell cycle. This process depends on nitric oxide (NO) production, release of hepatocyte …

Protocol for high-resolution separation of rodent myosin heavy chain isoforms in a mini-gel electrophoresis system

W Mizunoya, J Wakamatsu, R Tatsumi, Y Ikeuchi - Analytical Biochemistry, 2008 - Elsevier
Skeletal muscle comprises several fiber types classified based on their contractile and
metabolic properties. Skeletal muscle fiber types are classified according to their myosin heavy …

Possible implication of satellite cells in regenerative motoneuritogenesis: HGF upregulates neural chemorepellent Sema3A during myogenic differentiation

…, JE Anderson, Y Sato, W Mizunoya… - … of Physiology-Cell …, 2009 - journals.physiology.org
Regenerative coordination and remodeling of the intramuscular motoneuron network and
neuromuscular connections are critical for restoring skeletal muscle function and physiological …

Enhanced adult neurogenesis and angiogenesis and altered affective behaviors in mice overexpressing vascular endothelial growth factor 120

…, Y Yoshida, T Kino, K Ohnuki, W Mizunoya… - Journal of …, 2008 - Soc Neuroscience
Vascular endothelial growth factor (VEGF) is implicated as a molecular mediator for adult
neurogenesis and behavioral effects of antidepressant drugs. However, these potential roles of …

Matrix metalloproteinases are involved in mechanical stretch–induced activation of skeletal muscle satellite cells

…, S Okamoto, S Nonoshita, W Mizunoya… - Muscle & Nerve …, 2006 - Wiley Online Library
When skeletal muscle is stretched or injured, myogenic satellite cells are activated to enter
the cell cycle. This process depends on nitric oxide (NO) production, release of hepatocyte …

Mouse soleus (slow) muscle shows greater intramyocellular lipid droplet accumulation than EDL (fast) muscle: fiber type-specific analysis

…, R Tatsumi, Y Ikeuchi, W Mizunoya - Journal of muscle …, 2017 - Springer
Skeletal muscle is the main tissue of lipid metabolism and accordingly is critical for homeostasis
and energy production; however, the determinants of lipid accumulation in skeletal …