Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?
B Liu, M Li, Z Zhou, X Guan, Y Xiang - Journal of autoimmunity, 2020 - Elsevier
The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are among …
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are among …
[HTML][HTML] Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia
Background The initial cases of novel coronavirus (2019-nCoV)–infected pneumonia (NCIP)
occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We …
occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We …
Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in …
FC Zhu, YH Li, XH Guan, LH Hou, WJ Wang, JX Li… - The Lancet, 2020 - thelancet.com
Background A vaccine to protect against COVID-19 is urgently needed. We aimed to assess
the safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 (Ad5) …
the safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 (Ad5) …
[HTML][HTML] Cancer metastases: challenges and opportunities
X Guan - Acta pharmaceutica sinica B, 2015 - Elsevier
Cancer metastasis is the major cause of cancer morbidity and mortality, and accounts for
about 90% of cancer deaths. Although cancer survival rate has been significantly improved …
about 90% of cancer deaths. Although cancer survival rate has been significantly improved …
Treatment-related adverse events of PD-1 and PD-L1 inhibitors in clinical trials: a systematic review and meta-analysis
Importance Programmed cell death (PD-1) and programmed cell death ligand 1 (PD-L1)
inhibitors have been increasingly used in cancer therapy. Understanding the treatment-related …
inhibitors have been increasingly used in cancer therapy. Understanding the treatment-related …
Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind …
FC Zhu, XH Guan, YH Li, JY Huang, T Jiang, LH Hou… - The Lancet, 2020 - thelancet.com
… F-CZ was the principal investigator, and X-HG and J-YH were co-principal investigators. F-…
X-WW was responsible for statistical analysis. J-JX, B-SW, and JZ contributed to study …
X-WW was responsible for statistical analysis. J-JX, B-SW, and JZ contributed to study …
All-inorganic perovskite nanocrystal scintillators
… of multicolour X-ray scintillation from a series of all-inorganic perovskite nanocrystals and
demonstrate their use for ultrasensitive X-ray sensing and low-dose digital X-ray technology. …
demonstrate their use for ultrasensitive X-ray sensing and low-dose digital X-ray technology. …
[HTML][HTML] Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
…, P Sistonen, LA Aaltonen, M Nyström-Lahti, XY Guan… - Cell, 1993 - cell.com
Recent studies have shown that a locus responsible for hereditary nonpolyposis colorectal
cancer (HNPCC) is on chromosome 2p and that tumors developing in these patients contain …
cancer (HNPCC) is on chromosome 2p and that tumors developing in these patients contain …
[HTML][HTML] Fever with thrombocytopenia associated with a novel bunyavirus in China
…, JX Lu, WW Yin, H Zhou, XH Guan… - … England Journal of …, 2011 - Mass Medical Soc
Background Heightened surveillance of acute febrile illness in China since 2009 has led to
the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an unknown …
the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an unknown …
[HTML][HTML] Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement
Upland cotton is a model for polyploid crop domestication and transgenic improvement. Here
we sequenced the allotetraploid Gossypium hirsutum L. acc. TM-1 genome by integrating …
we sequenced the allotetraploid Gossypium hirsutum L. acc. TM-1 genome by integrating …