To maintain antimicrobial activity, frequent administration of conventional formulations of
many antibiotics with short half-life is necessary. Otherwise, concentration under MIC occurs …

Alzheimer's disease (AD) is the progressive development of fatal neurodegenerative diseases.
Owing to the unclearness of the pathogenesis of AD and the failure of the drug to cross …

The molecules that mediate neuron death in Alzheimer's disease (AD) are largely unknown.
We report that β-amyloid (Aβ), a death-promoting peptide implicated in the pathophysiology …

Wall-attached swirling ventilation is a new type of ventilation for the mechanized excavation
face. The dust control effect of the wall-attached swirling ventilation is affected by the forced-…

As a air-liquid two-phase flow nozzle, the internal-mixing air-assisted atomizer nozzle has
been widely used in the field of spray technology for dust reduction. Structural parameters are …

The pathogenesis of ischemic cerebrovascular disease has revealed that ischemia-reperfusion
(I/R) injury often leads to aggravation of metabolic oxidative stress and blood-brain …

Background A targeted drug nanoparticle (NP) delivery system has shown potential as a
possible cancer treatment. Given its merits, such as its selective distribution at tumor sites and …

Inflammation occurs throughout the progression of cerebral ischemia/reperfusion and
mediates myriads of pathological events following an ischemic insult. After ischemic stroke, …

Chronic diabetic wound injury is a serious syndrome of diabetes, and the treatment of this
syndrome is of great significance. Owing to metabolic abnormalities, diabetic wounds are …

Background The incidence of ischemic stroke in the context of vascular disease is high, and
the expression of growth-associated protein-43 (GAP43) increases when neurons are …