User profiles for Yoshiyuki Onuki

Yoshiyuki Onuki

Department of Neurosurgery, Jichi Medical University
Verified email at jichi.ac.jp
Cited by 460

Gene therapy improves motor and mental function of aromatic l-amino acid decarboxylase deficiency

…, K Nakamura, T Kubota, H Mizukami, S Ono, Y Onuki… - Brain, 2019 - academic.oup.com
In patients with aromatic l-amino acid decarboxylase (AADC) deficiency, a decrease in
catecholamines and serotonin levels in the brain leads to developmental delay and movement …

Hippocampal–cerebellar interaction during spatio-temporal prediction

Y Onuki, EJW Van Someren, CI De Zeeuw… - Cerebral …, 2015 - academic.oup.com
The hippocampus and cerebellum play a role in the process of temporal memory formation.
The interaction between these brain regions during the prediction of motor executions …

Selective enhancement of post-sleep visual motion perception by repetitive tactile stimulation during sleep

Y Onuki, O Lakbila-Kamal, B Scheffer… - Journal of …, 2022 - Soc Neuroscience
Tactile sensations can bias visual perception in the awake state while visual sensitivity is
known to be facilitated by sleep. It remains unknown, however, whether the tactile sensation …

[HTML][HTML] The sleeping cerebellum

CB Canto, Y Onuki, B Bruinsma, YD van der Werf… - Trends in …, 2017 - cell.com
We sleep almost one-third of our lives and sleep plays an important role in critical brain
functions like memory formation and consolidation. The role of sleep in cerebellar processing, …

[HTML][HTML] Impaired spatio-temporal predictive motor timing associated with spinocerebellar ataxia type 6

R Broersen, Y Onuki, AR Abdelgabar, CB Owens… - PLoS …, 2016 - journals.plos.org
Many daily life activities demand precise integration of spatial and temporal information of
sensory inputs followed by appropriate motor actions. This type of integration is carried out in …

Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula

…, MW Self, JC Peters, JK Possel, Y Onuki… - Elife, 2022 - elifesciences.org
Based on neuroimaging data, the insula is considered important for people to empathize
with the pain of others. Here, we present intracranial electroencephalographic (iEEG) …

[HTML][HTML] Comprehensive Metabolomic Analysis of IDH1R132H Clinical Glioma Samples Reveals Suppression of β-oxidation Due to Carnitine Deficiency

…, K Tominaga, E Sakashita, M Urabe, Y Onuki… - Scientific reports, 2019 - nature.com
Gliomas with Isocitrate dehydrogenase 1 (IDH1) mutation have alterations in several enzyme
activities, resulting in various metabolic changes. The aim of this study was to determine a …

Dopaminergic restoration of prefrontal cortico-putaminal network in gene therapy for aromatic l-amino acid decarboxylase deficiency

Y Onuki, S Ono, T Nakajima, K Kojima… - Brain …, 2021 - academic.oup.com
Aromatic l-amino acid decarboxylase (AADC) is an essential dopamine-synthesizing enzyme.
In children with AADC deficiency, the gene delivery of AADC into the putamen, which …

[PDF][PDF] Predictability alters information flow during action observation in human electrocorticographic activity

C Qin, F Michon, Y Onuki, Y Ishishita, K Otani, K Kawai… - Cell Reports, 2023 - cell.com
The action observation network (AON) has been extensively studied using short, isolated
motor acts. How activity in the network is altered when these isolated acts are embedded in …

Sleep to the beat: A nap favours consolidation of timing.

IM Verweij, Y Onuki, EJW Van Someren… - Behavioral …, 2016 - psycnet.apa.org
Growing evidence suggests that sleep is important for procedural learning, but few studies
have investigated the effect of sleep on the temporal aspects of motor skill learning. We …