Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B
Y Ohsaki, J Cheng, A Fujita, T Tokumoto… - Molecular biology of …, 2006 - Am Soc Cell Biol
Lipid esters stored in cytoplasmic lipid droplets (CLDs) of hepatocytes are used to synthesize
very low-density lipoproteins (VLDLs), into which apolipoprotein B (ApoB) is integrated …
very low-density lipoproteins (VLDLs), into which apolipoprotein B (ApoB) is integrated …
Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner
K Sołtysik, Y Ohsaki, T Tatematsu, J Cheng… - Journal of Cell …, 2020 - rupress.org
Nuclear lipid droplets (LDs) in hepatocytes are derived from precursors of very-low-density
lipoprotein in the ER lumen, but it is not known how cells lacking the lipoprotein secretory …
lipoprotein in the ER lumen, but it is not known how cells lacking the lipoprotein secretory …
PML isoform II plays a critical role in nuclear lipid droplet formation
Y Ohsaki, T Kawai, Y Yoshikawa, J Cheng… - Journal of Cell …, 2016 - rupress.org
Lipid droplets (LDs) in the nucleus of hepatocyte-derived cell lines were found to be
associated with premyelocytic leukemia (PML) nuclear bodies (NBs) and type I nucleoplasmic …
associated with premyelocytic leukemia (PML) nuclear bodies (NBs) and type I nucleoplasmic …
[HTML][HTML] Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis
K Sołtysik, Y Ohsaki, T Tatematsu, J Cheng… - Nature …, 2019 - nature.com
The origin and physiological significance of lipid droplets (LDs) in the nucleus is not clear.
Here we show that nuclear LDs in hepatocytes are derived from apolipoprotein B (ApoB)-free …
Here we show that nuclear LDs in hepatocytes are derived from apolipoprotein B (ApoB)-free …
[HTML][HTML] Lipid droplets: a classic organelle with new outfits
T Fujimoto, Y Ohsaki, J Cheng, M Suzuki… - Histochemistry and cell …, 2008 - Springer
Lipid droplets are depots of neutral lipids that exist virtually in any kind of cell. Recent studies
have revealed that the lipid droplet is not a mere lipid blob, but a major contributor not only …
have revealed that the lipid droplet is not a mere lipid blob, but a major contributor not only …
Lipid droplets: size matters
M Suzuki, Y Shinohara, Y Ohsaki… - Journal of electron …, 2011 - academic.oup.com
The lipid droplet (LD), an organelle that exists ubiquitously in various organisms, from bacteria
to mammals, has attracted much attention from both medical and cell biology fields. The …
to mammals, has attracted much attention from both medical and cell biology fields. The …
Biogenesis of cytoplasmic lipid droplets: from the lipid ester globule in the membrane to the visible structure
Y Ohsaki, J Cheng, M Suzuki, Y Shinohara… - … et Biophysica Acta (BBA …, 2009 - Elsevier
The cytoplasmic lipid droplet (CLD) and very low-density lipoprotein are generated from the
lipid ester synthesized in the endoplasmic reticulum. The lipid ester deposited between the …
lipid ester synthesized in the endoplasmic reticulum. The lipid ester deposited between the …
Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100
Y Ohsaki, J Cheng, M Suzuki, A Fujita… - Journal of cell …, 2008 - journals.biologists.com
Apolipoprotein B-100 (ApoB) is a major component of very-low-density lipoproteins, and is
deposited in a region around lipid droplets (LDs) called the `ApoB-crescent'. The ApoB-…
deposited in a region around lipid droplets (LDs) called the `ApoB-crescent'. The ApoB-…
[PDF][PDF] Open questions in lipid droplet biology
Y Ohsaki, M Suzuki, T Fujimoto - Chemistry & biology, 2014 - cell.com
Lipid droplets (LDs) have been the focus of intense research for the past decade because of
their active engagement in lipid metabolism and relationship with diseases. In contrast to …
their active engagement in lipid metabolism and relationship with diseases. In contrast to …
A pitfall in using BODIPY dyes to label lipid droplets for fluorescence microscopy
Y Ohsaki, Y Shinohara, M Suzuki, T Fujimoto - Histochemistry and cell …, 2010 - Springer
The lipid droplet (LD) has become a focus of intense research. Fluorescence labeling is
indispensable for the cell biological analysis of the LD, and a lipophilic fluorescence dye, …
indispensable for the cell biological analysis of the LD, and a lipophilic fluorescence dye, …