Bcl-xL is a well characterized death-suppressing molecule of the Bcl-2 family. Bcl-xL is
expressed in embryonic and adult neurons of the CNS and may play a critical role in preventing …

Objective: This study aims to evaluate protective effects of brief repetitive bilateral arm
ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic …

Astragalus membranaceus is a herbal medicine that has been used clinically in stroke patients
in China for decades, but its potential neuroprotective effect against ischemic brain injury …

Owing to a dramatic increase in average life expectancy and the Family Planning program
of the 1970s-1990s, China is rapidly becoming an aging society. Therefore, the investigation …

c-Jun N-terminal kinase (JNK) is an important stress-responsive kinase that is activated by
various forms of brain insults. In this study, we have examined the role of JNK activation in …

Peroxisome proliferator‐activated receptor gamma (PPAR‐γ) is a nuclear membrane‐associated
transcription factor that governs the expression of various inflammatory genes. PPAR‐γ …

Background and Purpose— We observed that microRNA-424 (miR-424) significantly
decreased in an miRNA profile of circulating lymphocytes of patients with ischemic stroke. The …

Background and Purpose— Long noncoding RNA H19 is repressed after birth, but can be
induced by hypoxia. We aim to investigate the impact on and underlying mechanism of H19 …

We previously showed that the microRNA miR-424 protects against permanent cerebral
ischemic injury in mice by suppressing microglia activation. This study investigated the role of …

Stroke is the number one cause of neurological dysfunction in adults and has a heavy
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …