[HTML][HTML] Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop

Y Yang, D Atasoy, HH Su, SM Sternson - Cell, 2011 - cell.com
Synaptic plasticity in response to changes in physiologic state is coordinated by hormonal
signals across multiple neuronal cell types. Here, we combine cell-type-specific …

[HTML][HTML] An excitatory ventral hippocampus to lateral septum circuit that suppresses feeding

P Sweeney, Y Yang - Nature communications, 2015 - nature.com
Previous research has focused on feeding circuits residing in the hindbrain and midbrain
that govern homeostatic or hedonic control of food intake. However, the feeding circuits …

Contribution of astrocytes to hippocampal long-term potentiation through release of d-serine

Y Yang, W Ge, Y Chen, Z Zhang… - Proceedings of the …, 2003 - National Acad Sciences
Repetitive correlated activation of pre- and postsynaptic neurons induced long-term
potentiation (LTP) of synaptic transmission among hippocampal neurons grown on a layer of …

[HTML][HTML] AGRP neurons modulate fasting-induced anxiolytic effects

…, G Sui, X Du, J Licinio, ML Wong, Y Yang - Translational …, 2019 - nature.com
Recent studies indicate that activation of hypothalamic Agouti-related protein (Agrp) neurons
can increase forage-related/repetitive behavior and decrease anxiety levels. However, the …

Spine expansion and stabilization associated with long-term potentiation

Y Yang, X Wang, M Frerking, Q Zhou - Journal of Neuroscience, 2008 - Soc Neuroscience
Stable expression of long-term synaptic plasticity is critical for the developmental refinement
of neural circuits and for some forms of learning and memory. Although structural …

[PDF][PDF] Astrocytes control food intake by inhibiting AGRP neuron activity via adenosine A1 receptors

L Yang, Y Qi, Y Yang - Cell reports, 2015 - cell.com
It is well recognized that feeding behavior in mammals is orchestrated by neurons within the
medial basal hypothalamus. However, it remains unclear whether food intake is also under …

Selective esterase–ester pair for targeting small molecules with cellular specificity

L Tian, Y Yang, LM Wysocki… - Proceedings of the …, 2012 - National Acad Sciences
Small molecules are important tools to measure and modulate intracellular signaling pathways.
A longstanding limitation for using chemical compounds in complex tissues has been the …

Delivery of AMPA receptors to perisynaptic sites precedes the full expression of long-term potentiation

Y Yang, X Wang, M Frerking… - Proceedings of the …, 2008 - National Acad Sciences
Trafficking of AMPA subtype glutamate receptors (AMPARs) from intracellular compartments
to synapses is thought to be a major mechanism underlying the expression of long-term …

An inhibitory septum to lateral hypothalamus circuit that suppresses feeding

P Sweeney, Y Yang - Journal of Neuroscience, 2016 - Soc Neuroscience
Feeding behavior is orchestrated by neural circuits primarily residing in the hypothalamus
and hindbrain. However, the relative influence of cognitive and emotional brain circuits to the …

[HTML][HTML] An excitatory ventromedial hypothalamus to paraventricular thalamus circuit that suppresses food intake

J Zhang, D Chen, P Sweeney, Y Yang - Nature communications, 2020 - nature.com
It is well recognized that ventromedial hypothalamus (VMH) serves as a satiety center in the
brain. However, the feeding circuit for the VMH regulation of food intake remains to be …