Blood-brain barrier breakdown during cerebral malaria: suicide or murder?

P Pino, Z Taoufiq, J Nitcheu… - Thrombosis and …, 2005 - thieme-connect.com
Cerebral malaria, one of the most serious complicatiof ons Plasmodium falciparum infection,
is characterized by the sequestration of parasitized red blood cells (PRBCs) in cerebral …

Hidden proteome of synaptic vesicles in the mammalian brain

Z Taoufiq, M Ninov, A Villar-Briones… - Proceedings of the …, 2020 - National Acad Sciences
… The mass spectrometer settings were as follow: full MS scan range 350 to 1,500 m/z with a
mass resolution of 70,000, 30-μs scan time, and automatic gain control set to 1.0E6 ions, and …

Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of held

K Eguchi, Z Taoufiq, O Thorn-Seshold… - Journal of …, 2017 - Soc Neuroscience
α-Synuclein is a presynaptic protein the function of which has yet to be identified, but its
neuronal content increases in patients of synucleinopathies including Parkinson's disease. …

Rho kinase inhibition in severe malaria: thwarting parasite-induced collateral damage to endothelia

Z Taoufiq, F Gay, J Balvanyos, L Ciceron… - The Journal of …, 2008 - academic.oup.com
Acute clinical manifestations of falciparum malaria, such as multiorgan failure and cerebral
malaria, occur unpredictably and lead to coma and death within hours if left untreated. …

Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer's disease synapse model

…, K Eguchi, HY Wang, T Miyasaka, L Guillaud, Z Taoufiq… - Elife, 2022 - elifesciences.org
Elevation of soluble wild-type (WT) tau occurs in synaptic compartments in Alzheimer’s disease.
We addressed whether tau elevation affects synaptic transmission at the calyx of Held in …

[HTML][HTML] Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage

Z Taoufiq, P Pino, N N'dilimabaka, I Arrouss, S Assi… - Malaria Journal, 2011 - Springer
Background The adhesion of Plasmodium falciparum parasitized red blood cell (PRBC) to
human endothelial cells (EC) induces inflammatory processes, coagulation cascades, …

[PDF][PDF] Maturation of a PKG-dependent retrograde mechanism for exoendocytic coupling of synaptic vesicles

K Eguchi, S Nakanishi, H Takagi, Z Taoufiq… - Neuron, 2012 - cell.com
At presynaptic terminals vesicular membranes are fused into plasma membrane upon
exocytosis and retrieved by endocytosis. During a sustained high-frequency transmission, …

Harbouring in the brain: a focus on immune evasion mechanisms and their deleterious effects in malaria and human African trypanosomiasis

…, FS Toure, Z Taoufiq… - International journal for …, 2006 - Elsevier
Malaria and human African trypanosomiasis represent the two major tropical vector-transmitted
protozoan infections, displaying different prevalence and epidemiological patterns. …

[HTML][HTML] P. falciparum Isolate-Specific Distinct Patterns of Induced Apoptosis in Pulmonary and Brain Endothelial Cells

N N'Dilimabaka, Z Taoufiq, S Zougbédé, S Bonnefoy… - PLoS …, 2014 - journals.plos.org
The factors implicated in the transition from uncomplicated to severe clinical malaria such
as pulmonary oedema and cerebral malaria remain unclear. It is known that alterations in …

Rho-kinase accelerates synaptic vesicle endocytosis by linking cyclic GMP-dependent protein kinase activity to phosphatidylinositol-4, 5-bisphosphate synthesis

Z Taoufiq, K Eguchi, T Takahashi - Journal of Neuroscience, 2013 - Soc Neuroscience
Rho-kinase plays diverse roles in cell motility. During neuronal development, Rho-kinase is
involved in neuronal migration, and in neurite outgrowth and retraction. Rho-kinase remains …