Nucleus Accumbens Modulation in Reward and Aversion
- Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University School of Medicine, Stanford, California 94305, USA
- Correspondence: malenka{at}stanford.edu
Abstract
The nucleus accumbens (NAc) is a key node of the brain's circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inputs that influence NAc activity in complex ways that are still poorly understood. Here, we briefly review current knowledge about the behavioral consequences of NAc modulation, focusing on recent studies that use novel techniques developed and implemented over the last decade.
- © 2018 Klawonn and Malenka; Published by Cold Spring Harbor Laboratory Press
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